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G-CSF R信息

英文名称:Colony Stimulating Factor 3 Receptor
中文名称:巨噬细胞集落刺激因子3受体
靶点别称:G-CSF-R,GCSFR,G-CSF receptor,Granulocyte colony-stimulating factor receptor,CD_antigen=CD114,CSF3R
上市药物数量:96
临床药物数量:48
最高研发阶段:批准上市

G-CSF R产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
GCR-H5223
Human
Human G-CSF R / CD114 Protein, His Tag
GCR-H5250
Human
Human-GCSFR-CD114-Protein-C-Fc-Tag
GCR-H82E4
Human
Biotinylated Human G-CSF R / CD114 Protein, Avitag,His Tag

G-CSF R 分子别名

CSF3R,CD114,GCSFR

G-CSF R 分子背景

Granulocyte Colony Stimulating Factor Receptor (G-CSFR) is also known as Cluster of Differentiation 114 (CD114), CSF3R and GCSF, is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF), a cytokine that plays a critical role in the regulation of the activation, proliferation, differentiation, and survival of the neutrophilic granulocyte lineage. G-CSFR belongs to a family of cytokine receptors known as the hematopoietin receptor family. This type I  membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type I II (FNIII) domains in the extracellular region. G-CSFR is present mainly on precursor cells in the bone marrow, and, in response to stimulation by G-CSF, initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages. G-CSFR mediates the specific effect of GCSF through activating a variety of intracellular signaling cascades, including the Jak/Stat, PI3/Akt, Ras-Raf-MAP kinase, and Src family kinase pathways, and thus functions in defense against infection, inflammation and repair, and in the maintenance of steady state hematopoiesis. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. Mutations in the intracellular part of this receptor are also associated with certain types of leukemia.

G-CSF R 参考文献

G-CSF R上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Recombinant human granulocyte colony-stimulating factor (Harbin Pharmaceutical Group Bioengineering) 重组人粒细胞刺激因子注射液 批准上市 哈药集团 嗜中性粒细胞减少症
Filgrastim biosimilar (Blau Pharmaceuticals) 非格司亭生物类似药(Blau Pharmaceuticals) 批准上市 Blau Pharmaceuticals 嗜中性粒细胞减少症
Filgrastim biosimilar (Center of Molecular Immunology) 非格司亭生物类似药(Center of Molecular Immunology) 批准上市 Center of molecular immunology 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Emcure Pharmaceuticals) 批准上市 Emcure 嗜中性粒细胞减少症
Filgrastim biosimilar (Takeda) 非格司亭生物类似药(武田) 批准上市 武田 Filgrastim biosimilar (Takeda) 日本 嗜中性粒细胞减少症 武田 2013-02-28 00:00:00.0 嗜中性粒细胞减少症
Filgrastim biosimilar (Zydus Cadila) 非格司亭生物类似药(Zydus Cadila) 批准上市 Zydus cadila 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Juta Pharma) 非格司亭生物类似物(Juta Pharma) 批准上市 Juta Pharma pegfilgrastim ema

Reduction in the duration of neutropenia and the incidence of febrile neutropenia in adult patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplast

Juta Pharma GmbH 2019-04-26 嗜中性粒细胞减少症
Filgrastim biosimilar(Pooyesh Darou Pharmaceuticals) 非格司亭生物类似药(Pooyesh Darou Pharmaceuticals) G-CSF,G CSF,GCSF 批准上市 Pooyesh Darou 骨髓增生异常综合征, 嗜中性粒细胞减少症, 急性骨髓性白血病, 淋巴瘤
Filgrastim biosimilar (Hospira) 非格司亭生物类似药(Hospira) PLD-108,PLD108 批准上市 Hospira filgrastim ema

Filgrastim is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chron

Pfizer Europe MA EEIG 2010-06-07 嗜中性粒细胞减少症 详情
Recombinant Human Granulocyte Colony-stimulating Factor (Wuzhong Group) 重组人粒细胞刺激因子注射液 批准上市 江苏吴中医药苏州制药厂 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Apotex/Intas) 非格司亭生物类似药 (Apotex/Intas) 批准上市 Intas Biopharmaceuticals, Apotex, SciVac Ltd filgrastim ema

Grastofil is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chroni

Apotex Europe BV 2013-10-17 嗜中性粒细胞减少症
Filgrastim biosimilar (Veropharm) 非格司亭生物类似药(Veropharm) 批准上市 雅培 嗜中性粒细胞减少症
Filgrastim biosimilar (Zenotech Laboratories) 非格司亭生物类似药(Zenotech Laboratories) 批准上市 Zenotech laboratories 嗜中性粒细胞减少症, 癌症
Filgrastim biosimilar (AqVida) 非格司亭生物类似药(AqVida) 批准上市 AqVida 嗜中性粒细胞减少症
Lipegfilgrastim XM-22,XM22 批准上市 梯瓦 lipegfilgrastim ema

Reduction in the duration of neutropenia and the incidence of febrile neutropenia in adult patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplast

Teva B.V. 2013-07-25 嗜中性粒细胞减少症 详情
Pegfilgrastim-jmdb MYL-1401H,MYL1401H; MYL-1401-H 批准上市 Biocon, 迈兰制药 FULPHILA fda MYLAN GMBH 2018-06-04 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Zydus Cadila) 批准上市 Zydus cadila 嗜中性粒细胞减少症
Filgrastim biosimilar (Pharmapark) 非格司亭生物类似药(Pharmapark) 批准上市 Pharmapark 嗜中性粒细胞减少症
Filgrastim biosimilar (Elea) 非格司亭生物类似药(Elea) 批准上市 Elea 嗜中性粒细胞减少症
Filgrastim biosimilar (Chandra Bhagat Pharma) 非格司亭生物类似药(Chandra Bhagat Pharma) 批准上市 Chandra Bhagat Pharma(CBC) 癌症
GCPGC MG-1107 批准上市 Green Cross 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (GeneScience Pharmaceuticals) 非格司亭生物类似药(金赛药业) 批准上市 金赛药业 Recombinant Human Granulocyte Colony-stimulating Factor Injection cfda 嗜中性粒细胞减少症 2015-08-18 嗜中性粒细胞减少症
Filgrastim biosimilar (Chengdu Institute of Biological Products) 非格司亭生物类似药(成都生物制品研究所) 批准上市 成都生物制品研究所 嗜中性粒细胞减少症
Filgrastim biosimilar (Shandong Quangang Pharmaceutical) 非格司亭生物类似药(山东泉港药业) 批准上市 山东泉港药业 嗜中性粒细胞减少症
Filgrastim biosimilar (Sedico) 非格司亭生物类似药(Sedico) 批准上市 Sedico 嗜中性粒细胞减少症
Filgrastim biosimilar (Xiamen Amoytop Biotech) 非格司亭生物类似药(厦门特宝生物) 批准上市 厦门特宝生物工程股份有限公司 Recombinant Human Granulocyte Colony-Stimulating Factor Injection cfda 嗜中性粒细胞减少症 2015-09-24 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Accord Healthcare) 批准上市 Accord Healthcare, Intas Biopharmaceuticals pegfilgrastim ema

Reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syn

Accord Healthcare S.L.U. 2018-09-21 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Zydus-Cadila Group) 批准上市 Zydus cadila 嗜中性粒细胞减少症
Recombinant human granulocyte colony-stimulating Factor (Shenzhen Xinpeng Bio-tech) 重组人粒细胞刺激因子注射液(未名新鹏) 批准上市 深圳新鹏生物工程有限公司 Recombinant Human Granulocyte Colony-stimulating Factor Injection cfda 嗜中性粒细胞减少症 2015-06-01 嗜中性粒细胞减少症
Filgrastim biosimilar (Nanogen) 非格司亭生物类似药(Nanogen) 批准上市 Nanogen Biopharmaceutical Co 嗜中性粒细胞减少症
Filgrastim biosimilar (Beijing SL Pharmaceutical) 非格司亭生物类似药(北京双鹭药业) 批准上市 北京双鹭药业 嗜中性粒细胞减少症
Filgrastim biosimilar (Apexcela) 非格司亭生物类似药(Apexcela) Leuco-Plus-300 批准上市 Apexcela, Siam Bioscience 嗜中性粒细胞减少症
Nartograstim KW-2228; ND-28; PE-2601,KW2228 批准上市 协和发酵麒麟, 养乐多 Nartograstim 日本 嗜中性粒细胞减少症 养乐多 1994-04-01 00:00:00.0 嗜中性粒细胞减少症
Filgrastim biosimilar (SICOR Biotech) 非格司亭生物类似药(SICOR Biotech) 批准上市 梯瓦 嗜中性粒细胞减少症
Filgrastim biosimilar (Dong-A) 非格司亭生物类似药(Dong-A) DA-3030 批准上市 Dong-A Pharmaceutical 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Landsteiner) 非格司亭生物类似药(Landsteiner) 批准上市 Landsteiner Scientific 嗜中性粒细胞减少症
Filgrastim-sndz EP-2006,EP2006 批准上市 山德士 filgrastim ema
  • Reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and my
Hexal AG 2009-02-05 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Dong-A ST) DA-3031 批准上市 Dong-A Pharmaceutical 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (RPG Life Sciences) 非格司亭生物类似药(RPG Life Sciences) 批准上市 RPG Life Sciences 嗜中性粒细胞减少症
Filgrastim biosimilar (Hangzhou Jiuyuan Gene Engineering) 非格司亭生物类似药(杭州九源基因工程) 批准上市 杭州九源基因工程 Recombinant Human Granulocyte Colony Stimulating Factor Injection cfda 嗜中性粒细胞减少症 2015-11-04 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (CinnaGen) 批准上市 CinnaGen 嗜中性粒细胞减少症
Filgrastim biosimilar (Siam Bioscience) 非格司亭生物类似药(Siam Bioscience) 批准上市 Siam Bioscience 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Amega Biotech) 批准上市 Amega Biotech 嗜中性粒细胞减少症
Filgrastim 非格司亭 KRN-8601; REC-G-CSF; r-metHuG-CSF; rhGCSF (Amgen/Kyowa Hakko Kirin),KRN8601 批准上市 安进, 协和发酵麒麟 Neupogen hma 嗜中性粒细胞减少症 Amgen Europe B.V.
Minervum 7061
4817 ZK Breda
The Netherlands
1991-03-15 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Dr Reddy's Laboratories) DRL_PG 批准上市 Dr.Reddy's Laboratories 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Nanogen Biopharmaceutical) 批准上市 Nanogen Biopharmaceutical Co 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Dr Reddy's Laboratories) 非格司亭生物类似药(Dr Reddy's Laboratories) 批准上市 Dr Reddys Laboratories 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Cinfa Biotech) B-12019,B12019; B 12019 批准上市 Cinfa Biotech, 萌蒂制药有限公司 pegfilgrastim ema

To reduce the duration of neutropenia and the incidence of febrile neutropenia due to chemotherapy

Cinfa Biotech S.L. 2018-11-20 嗜中性粒细胞减少症 详情
Pegfilgrastim KRN-125; R-1471; SD-01; SD/01 批准上市 安进, 协和发酵麒麟 NEULASTA fda 嗜中性粒细胞减少症 AMGEN 2002-01-31 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Qilu Pharmaceutical) 非格司亭生物类似药(齐鲁制药) 批准上市 齐鲁制药 嗜中性粒细胞减少症
Filgrastim biosimilar (Biosidus) 非格司亭生物类似药(Biosidus) 批准上市 Biosidus 嗜中性粒细胞减少症
Pegylated recombinant human granulocyte colony stimulating factor (CSPC Pharma) 聚乙二醇化重组人粒细胞刺激因子 批准上市 石药集团 PEGylated Recombinant Human Granulocyte Colony-Stimulating Factor Injection cfda 嗜中性粒细胞减少症 2016-07-05 嗜中性粒细胞减少症 详情
Tbo-filgrastim XM-02; TKN-732,XM02 批准上市 梯瓦, 日本化药株式会社 filgrastim ema

Biograstim is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chron

AbZ-Pharma GmbH 2008-09-15 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Sudershan Biotech) 非格司亭生物类似药(Sudershan Biotech) 批准上市 Sudershan Biotech Ltd 嗜中性粒细胞减少症
Lenograstim 来格司亭 rG-CSF 批准上市 中外制药 Lenograstim 日本 嗜中性粒细胞减少症 中外制药 1991-10-04 00:00:00.0 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (CIGB/Heber Biotec) 非格司亭生物类似药(CIGB/Heber Biotec) 批准上市 Center for Genetic Engineering and Biotechnology, Heber Biotec 嗜中性粒细胞减少症
Lenograstim biosimilar (Biosidus) 批准上市 Biosidus 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (AryaTinaGene) 批准上市 AryaTinaGene Biopharmaceuticals 发热性中性粒细胞减少症
Filgrastim biosimilar (Zuventus Healthcare) 非格司亭生物类似药(Zuventus Healthcare) 批准上市 Zuventus Healthcare 嗜中性粒细胞减少症
Pegfilgrastim (Dompé Biotec) 批准上市 Dompé Biotec pegfilgrastim ema

Reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syn

Dompé Biotec S.p.A. 2002-08-22 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Qilu Pharmaceuticals) 聚乙二醇化重组人粒细胞刺激因子(齐鲁制药) PEG-rhG-CSF (Qilu Pharmaceuticals) 批准上市 齐鲁制药 Pegylated Recombinant Human Granulocyte Colony-stimulating Factor Injection cfda 嗜中性粒细胞减少症 2015-08-18 嗜中性粒细胞减少症 详情
Recombinant human granulocyte colony-stimulating factor (Shandong Kexing Bioproducts Co Ltd) 重组人粒细胞刺激因子 批准上市 山东科兴生物制品有限公司 嗜中性粒细胞减少症
Filgrastim biosimilar (Unilab) 非格司亭生物类似药(Unilab) 批准上市 Unilab 嗜中性粒细胞减少症
Filgrastim biosimilar (Biocon) 非格司亭生物类似药(Biocon) 批准上市 Biocon BioPharmaceuticals, 迈兰制药 嗜中性粒细胞减少症
Filgrastim biosimilar (Institute of Medical Biology Chinese Academy of Medical Sciences) 非格司亭生物类似药(中国医学科学院医学生物学研究所) 批准上市 中国医学科学院医学生物学研究所 Recombinant Human Granulocyte-Macrophage Colony Stimulating Factou Injection cfda 白细胞减少症, 骨髓增生异常综合征, 嗜中性粒细胞减少症 2015-09-19 骨髓增生异常综合征, 白细胞减少症, 嗜中性粒细胞减少症
Empegfilgrastim BCD-017 批准上市 Biocad 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Fresenius Kabi Oncology) 非格司亭生物类似药(Fresenius Kabi Oncology) 批准上市 Fresenius Kabi 嗜中性粒细胞减少症
Filgrastim biosimilar (RAS Lifesciences) 非格司亭生物类似药(RAS Lifesciences) 批准上市 RAS Lifesciences 嗜中性粒细胞减少症
Pegfilgrastim-cbqv (Coherus BioSciences) CHS-1701 批准上市 Coherus Biosciences pegfilgrastim ema

Reduction in the duration of neutropenia and the incidence of febrile neutropenia in adult patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplast

ERA Consulting GmbH 2018-09-21 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (CJ Corp) 非格司亭生物类似药(CJ Corp) 批准上市 CJ, Reliance GeneMedix 嗜中性粒细胞减少症
Filgrastim biosimilar (NCPC GeneTech Biotechnology Development) 非格司亭生物类似药(NCPC GeneTech Biotechnology Development) 批准上市 华北制药- 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Intas Biopharmaceuticals) INTP-5 批准上市 Intas Biopharmaceuticals, Apotex 嗜中性粒细胞减少症
Filgrastim biosimilar (Eurofarma) 非格司亭生物类似药(Eurofarma) 批准上市 Eurofarma 嗜中性粒细胞减少症
Filgrastim biosimilar (Claris Lifesciences) 非格司亭生物类似药(Claris Lifesciences) 批准上市 Claris Lifesciences 嗜中性粒细胞减少症
Filgrastim biosimilar (Biolotus Biotech) 非格司亭生物类似药(Biolotus Biotech) 批准上市 Biolotus 嗜中性粒细胞减少症
Filgrastim biosimilar (Probiomed) 非格司亭生物类似药(Probiomed) 批准上市 Probiomed 嗜中性粒细胞减少症
Filgrastim biosimilar (Emcure Pharmaceuticals) 非格司亭生物类似药(Emcure Pharmaceuticals) 批准上市 Emcure 嗜中性粒细胞减少症
Recombinant human granulocyte stimulating factor (CSPC Pharma) 重组人粒细胞刺激因子(石药集团) 批准上市 石药集团 Recombinant Human Granulocyte Colony-stimulating Factor Injection cfda 嗜中性粒细胞减少症 2015-02-04 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Lupin) 非格司亭生物类似药(Lupin) 批准上市 Lupin 嗜中性粒细胞减少症
Filgrastim biosimilar(PT Kalbe) rh-G-CSF (Kalbe Farma),rh G CSF (Kalbe Farma),rhGCSF (Kalbe Farma) 批准上市 Kalbe Farma 嗜中性粒细胞减少症
Filgrastim biosimilar (Pharmstandard/Masterclone/CJSC Generium) 非格司亭生物类似药(Pharmstandard/Masterclone/CJSC Generium) 批准上市 Pharmstandard, CJSC Generium, Masterclone 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Lupin) 批准上市 Lupin 嗜中性粒细胞减少症
Filgrastim biosimilar (Reliance Life Sciences) 非格司亭生物类似药(Reliance Life Sciences) 批准上市 Reliance Life Sciences 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Harvest Moon Pharmaceuticals/PanPharmaceuticals) 聚乙二醇非格司亭生物仿制药(Harvest Moon Pharmaceuticals/PanPharmaceuticals) 批准上市 Harvest Moon, PanPharmaceutical 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Sandoz) 聚乙二醇非格司亭(山德士) LAEP-2006,LA-EP-2006 ,LA-EP2006 批准上市 山德士 pegfilgrastim ema

Reduction in the duration of neutropenia and the incidence of febrile neutropenia in adult patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid l

Sandoz GmbH 2018-11-22 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Fuji Pharmaceutical/Mochida/Gene Techno Science) 非格司亭生物类似药(Fuji Pharmaceutical/Mochida/Gene Techno Science) FSK-0808; GBS-001 批准上市 Gene Techno Science, 持田制药, Fuji Pharmaceutical Filgrastim biosimilar (Fuji Pharmaceutical/Mochida/Gene Techno Science) 日本 嗜中性粒细胞减少症 持田制药,Fuji Pharmaceutical 2012-11-21 00:00:00.0 嗜中性粒细胞减少症
Filgrastim biosimilar (Laboratorios AC Farma) 非格司亭生物类似药(Laboratorios AC Farma) 批准上市 Laboratorios AC Farma 嗜中性粒细胞减少症
Filgrastim biosimilar (Laboratorio Varifarma) 非格司亭生物类似药(Laboratorio Varifarma) 批准上市 Laboratorio Varifarma, Laboratorio Pablo Cassara 嗜中性粒细胞减少症
Filgrastim biosimilar (Incepta Pharmaceuticals) 非格司亭生物类似药(Incepta Pharmaceuticals) 批准上市 Incepta Pharmaceuticals 嗜中性粒细胞减少症
Filgrastim biosimilar (Chalver Laboratorios) 非格司亭生物类似药(Chalver Laboratorios) 批准上市 Chalver Laboratorios 嗜中性粒细胞减少症
Recombinant human granulocyte colony-stimulating factor (Shanghai Sunway Biotech) 重组人粒细胞集落刺激因子(上海三维生物) 批准上市 上海三维生物技术有限公司 cfda 嗜中性粒细胞减少症 2015-06-29 嗜中性粒细胞减少症
Mecapegfilgrastim 硫培非格司亭 HHPG-19K 批准上市 江苏恒瑞 Mecapegfilgrastim Injection cfda 嗜中性粒细胞减少症 2018-05-08 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Amega Biotech) 非格司亭生物类似药(Amega Biotech) 批准上市 Amega Biotech 嗜中性粒细胞减少症
Filgrastim biosimilar (Neiss Labs) 非格司亭生物类似药(Neiss Labs) 批准上市 Neiss Labs 嗜中性粒细胞减少症
Recombinant human granulocyte colony stimulating Factor (Beijing Four Rings Bio-Pharmaceutical) 重组人粒细胞刺激因子注射液 批准上市 北京四环生物制药有限公司 嗜中性粒细胞减少症
Filgrastim biosimilar (Accord Healthcare) 非格司亭生物类似药(Accord Healthcare) 批准上市 Accord Healthcare filgrastim ema

Accofil is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chronic

Accord Healthcare S.L.U. 2014-09-17 嗜中性粒细胞减少症

G-CSF R临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Interleukin-1 alpha (Amgen/Roche) 临床二期 安进, 罗氏 嗜中性粒细胞减少症, 血小板减少症, 辐射损伤, 霍奇金淋巴瘤, 黑色素瘤
Albumin-granulocyte colony stimulating factor (Beijing BioFortune/Tianjin SinoBiotech) rHSA/GCSF; SFR-9314 临床二期 天津溥瀛生物, 北京美福源 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Biogenomics) rH-GCSF,rH GCSF 临床一期 Biogenomics 嗜中性粒细胞减少症
Granulocyte colony-stimulating factor (Shire) 临床一期 Shire 嗜中性粒细胞减少症 详情
Benegrastim F-627; rh G-CSF Fc Fusion Protein 临床三期 旭华生物, 健能隆医药 嗜中性粒细胞减少症, 乳腺癌 详情
Pegfilgrastim biosimilar (Pfenex) 临床前 Pfenex 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Virchow Group) PEG Neutrogen 临床一期 Virchow Group 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Siam Bioscience) 临床前 Siam Bioscience 嗜中性粒细胞减少症
Filgrastim biosimilar (Adello Biologics) BLA 申请 Adello Biologics 嗜中性粒细胞减少症
Filgrastim biosimilar (Merck) INS-19; MK-4214 临床三期 Insmed, 默沙东 嗜中性粒细胞减少症
Pegnartograstim RO-258315 临床一期 罗氏 干细胞移植
Pegfilgrastim biosimilar (Fresenius SE) MSB-11455 临床一期 默克雪兰诺 癌症 详情
Pegfilgrastim biosimilar (Beijing SL Pharmaceutical) 临床阶段不明 北京双鹭药业 嗜中性粒细胞减少症
Filgrastim biosimilar (Bionaturis) 临床前 Bionaturis 嗜中性粒细胞减少症, 溶酶体贮积症
Filgrastim biosimilar(Shandong Xinshidai Biotech) BLA 申请 鲁南制药集团 免疫性疾病
GW-003 GW-003 临床一期 江苏泰康生物医药有限公司 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Pfizer) HSP-130 临床二期 辉瑞 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Tianjin Pegylatt Biotechnology) 临床一期 中科院过程工程研究所, 天津派格生物技术有限公司, 天津药物研究院 发热性中性粒细胞减少症, 嗜中性粒细胞减少症
Filgrastim biosimilar (MenoGenix) MNGX-100 临床一期 MenoGeniX 绝经期症状
Filgrastim biosimilar (Mycenax Biotech) BLA 申请 永昕生物医药 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Merck) MK-6302,INS-20 临床一期 Insmed, 默沙东 嗜中性粒细胞减少症
Recombinant G-CSF (Yuhan) 临床三期 Yuhan Corporation 嗜中性粒细胞减少症
CSL-324 CSL-324 临床一期 MuriGen, CSL 炎症, 类风湿性关节炎 详情
Granulocyte colony stimulating factor (Xenetic Biosciences/SynBio) SYN-20111504-RU 临床二期 Lipoxen Technologies, Serum Institute of India, SynBio, Xenetic Biosciences 嗜中性粒细胞减少症 详情
GX-G03 G-CSF-hyFc; GCSF-hFc; GX-G03; GX-G3 临床二期 Genexine, 保宁, Ilkogen 嗜中性粒细胞减少症 详情
GM-CSF / IL3 fusion protein 临床申请 上海兆安医学科技有限公司, 北京依格斯医药技术开发有限公司 不明
Eflapegrastim HM-10460A; HNK-460; LAPS-GCSF; SPI-2012 临床三期 韩美, Spectrum Pharmaceuticals 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Bio-Ker) 临床一期 Bio-Ker 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Jiangsu Aosaikang Pharmaceutical) 临床一期 江苏奥赛康药业 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (PharmaEssentia) PEG-GCSF 临床一期 PharmaEssentia 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Tanvex BioPharma) TX-01 BLA 申请 Tanvex BioPharma 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Eurofarma) 临床一期 Eurofarma 嗜中性粒细胞减少症 详情
Pegfilgrastim ANF PEG-G-CSF-ANF 临床二期 Prolong Pharmaceuticals 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Bio-Ker) BK-0023 临床三期 Bio-Ker 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Hangzhou Jiuyuan Gene Engineering) 临床二期 杭州九源基因工程 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Gedeon Richter) RGB-02,RGB02; RGB 02 BLA 申请 吉瑞大药厂 嗜中性粒细胞减少症 详情
SBC-014 AES-014; AVI-014; SBC-014 临床三期 亚力兄制药 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (USV) 临床三期 USV 嗜中性粒细胞减少症
pegfilgrastim biosimilar (NAL Pharma) NAL-3760 临床前 NAL Pharma 嗜中性粒细胞减少症
Balugrastim (CoGenesys) CG-10639; ALB-rG-CSF; G-CSF-HAS; HSA-rG-CSF 临床三期 CoGenesys, 梯瓦 嗜中性粒细胞减少症
Milodistim (Amgen) GM-CSF/IL-3;PIXY-321,PIXY 321 临床三期 安进, 惠氏 嗜中性粒细胞减少症, 血小板减少症, 化疗引起的血小板减少症
Filgrastim biosimilar (Raichem Lifesciences) 临床阶段不明 Raichem lifesciences 嗜中性粒细胞减少症
SC-70935 SC-70935 临床三期 Pharmacia Corporation 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Adello Biologics) 临床一期 Adello Biologics 嗜中性粒细胞减少症 详情
Pegfilgrastim biosimilar (Shandong New Time) 临床三期 鲁南制药集团 嗜中性粒细胞减少症
Y-branched pegylated recombinant human granulocyte colony stimulating factor YPEG-rhG-CSF 临床二期 厦门特宝生物工程股份有限公司, BioGeneric 嗜中性粒细胞减少症 详情
Filgrastim biosimilar (Virchow Group) Neutrogen 临床三期 Virchow Group 嗜中性粒细胞减少症
Pegfilgrastim biosimilar (Reliance Life Sciences) R-TPR-029 临床三期 Reliance Life Sciences 嗜中性粒细胞减少症

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