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Fc epsilon RI alpha产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
FCA-H5228
Human
Human Fc epsilon RI alpha Protein, His Tag
 
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Fc epsilon RI alpha 分子别名

FCER1A,FCE1A,FcERI

Fc epsilon RI alpha 分子背景

High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.

Fc epsilon RI alpha 参考文献

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