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CD48信息

英文名称:Cluster of Differentiation 48
中文名称:分化簇48
靶点别称:CD48,HCD48,SLAMF2,SLAM family member 2,Signaling lymphocytic activation molecule 2,TCT.1,Leukocyte antigen MEM-102,BCM1,B-lymphocyte activation marker BLAST-1,MEM-102,BCM1 surface antigen,BLAST1,MCD48
上市药物数量:0
临床药物数量:2
最高研发阶段:临床一期

CD48产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
BC1-H5226
Human
Recombinant Human CD48 / SLAMF2 / BCM1 Protein
BC1-H5255
Human
Human CD48 / SLAMF2 Protein, Fc Tag
BC1-H5258
Human
Human CD48 / SLAMF2 Protein, Mouse IgG2a Fc Tag, low endotoxin

CD48 分子别名

CD48,BCM1,SLAMF2,BLAST,BLAST1,MEM-102,TCT.1,BCM-1,SLAMF-2,BLAST-1

CD48 分子背景

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

CD48 参考文献

CD48临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Anti-CD48 monoclonal antibody WM-63 临床一期 Nonindustrial source 慢性淋巴细胞白血病
SGN-CD48A SGN-CD48A 临床一期 Seattle Genetics 多发性骨髓瘤 详情

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