CD37 靶点蛋白|抗体药物|临床药物信息

CD37信息

英文名称：Leukocyte antigen CD37
中文名称：白细胞抗原CD37
靶点别称：Tspan-26，TSPAN26，Tetraspanin-26，CD37

上市药物数量：0
临床药物数量：7
最高研发阶段：临床二期

CD37产品列表

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产品库

在线 (1)

物种

Human (1)

标签

Fc Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
CD7-H526x	Human	Human CD37 Protein,N-Fc Tag

CD37 分子别名

CD37,Tspan-26,TSPAN26

CD37 分子背景

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

CD37 参考文献

CD37临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
CAR-37 T cell therapy (Massachusetts General Hospital)		临床一期	马萨诸塞总医院	B细胞淋巴瘤, 血液系统恶性肿瘤, 白血病, 淋巴瘤, 非霍奇金淋巴瘤, T细胞淋巴瘤	详情
BI-836826	BI-836826; mAb-37.1; mAb-37.2	临床二期	勃林格殷格翰, 吉利德	慢性淋巴细胞白血病, 弥漫大B细胞淋巴瘤, 非霍奇金淋巴瘤	详情
Naratuximab emtansine	IMGN-529; K7153A-SMCC-DM1	临床二期	ImmunoGen	慢性淋巴细胞白血病, 非霍奇金淋巴瘤	详情
212Pb-NNV-003	NNV-013; 212Pb-NNV003	临床前	Orano Med, Nordic Nanovector	慢性淋巴细胞白血病, 非霍奇金淋巴瘤
Otlertuzumab	TRU-016	临床二期	Emergent	慢性淋巴细胞白血病, 非霍奇金淋巴瘤	详情
Lutetium (177lu) lilotomab satetraxetan	177Lu-DOTA-HH1	临床二期	Nordic Nanovector	弥漫大B细胞淋巴瘤, 滤泡性淋巴瘤, 非霍奇金淋巴瘤	详情
AGS-67E	AGS-67E,AGS67E	临床一期	Agensys	淋巴细胞性白血病, 慢性淋巴细胞白血病, 毛细胞白血病, 急性骨髓性白血病, 非霍奇金淋巴瘤	详情

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CD37 重组蛋白