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CD37信息

英文名称:Leukocyte antigen CD37
中文名称:白细胞抗原CD37
靶点别称:Tspan-26,TSPAN26,Tetraspanin-26,CD37
上市药物数量:0
临床药物数量:6
最高研发阶段:临床二期

CD37产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CD7-H526x
Human
Human CD37 Protein,N-Fc Tag

CD37 分子别名

CD37,Tspan-26,TSPAN26

CD37 分子背景

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

CD37 参考文献

CD37临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
BI-836826 BI-836826; mAb-37.1; mAb-37.2 临床二期 勃林格殷格翰, 吉利德 慢性淋巴细胞白血病, 弥漫大B细胞淋巴瘤, 非霍奇金淋巴瘤 详情
Naratuximab emtansine IMGN-529; K7153A-SMCC-DM1 临床二期 ImmunoGen 慢性淋巴细胞白血病, 非霍奇金淋巴瘤 详情
212Pb-NNV-003 NNV-013; 212Pb-NNV003 临床前 Orano Med, Nordic Nanovector 慢性淋巴细胞白血病, 非霍奇金淋巴瘤
Otlertuzumab TRU-016 临床二期 Emergent 慢性淋巴细胞白血病, 非霍奇金淋巴瘤 详情
Lutetium (177lu) lilotomab satetraxetan 177Lu-DOTA-HH1 临床二期 Nordic Nanovector 弥漫大B细胞淋巴瘤, 滤泡性淋巴瘤, 非霍奇金淋巴瘤 详情
AGS-67E AGS-67E,AGS67E 临床一期 Agensys 淋巴细胞性白血病, 慢性淋巴细胞白血病, 毛细胞白血病, 急性骨髓性白血病, 非霍奇金淋巴瘤 详情

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