搜索
 > 【B7-H2】重组蛋白信息

B7-H2产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
B72-H5221
Human
Human B7-H2 / ICOSLG Protein, His Tag
B72-H5254
Human
Human B7-H2 / ICOSLG Protein, Fc Tag
B72-M52H7
Mouse
Mouse B7-H2 / ICOSLG Protein, His Tag
B72-M5258
Mouse
Mouse B7-H2 / ICOSLG Protein, Fc Tag
B72-C525b
Cynomolgus
Cynomolgus B7-H2 / ICOSLG Protein, Fc Tag
B72-C52Hb
Cynomolgus
Cynomolgus B7-H2 / ICOSLG Protein, His Tag
 
评论(0)
 

B7-H2 Molecule Synonym Name

ICOSLG,B7-H2,B7H2,B7RP-1,B7RP1,CD275,GL50,ICOS-L,ICOSL,LICOS,ICOS ligand

B7-H2 分子背景

ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

B7-H2 参考文献

消息提示

请输入您的联系方式,再点击提交!

确定