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Human S100P / S100E Protein, Tag Free

分子别名(Synonym)

S100P,S100E,MIG9

表达区间及表达系统(Source)

Human S100P, Tag Free (S1P-H5110) is expressed from E.coli cells. It contains AA Met 1 - Lys 95 (Accession # AAH06819).

Predicted N-terminus: Met

蛋白结构(Molecular Characterization)

Unconjugated(Met  1 -  Lys 95) AAH06819

This protein carries no "tag".

The protein has a calculated MW of 10.4 kDa. The protein migrates as 10.4 kDa under reducing (R) condition (SDS-PAGE).

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human S100P, Tag Free (Cat. No. S1P-H5110) SDS-PAGE gel

Human S100P, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

背景(Background)

S100 calcium-binding protein P (S100P),a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E,which contains two EF-hand domains. As for subunit structure,S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore,S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

 

前沿进展

 
货号/价格

S1P-H5110-100ug / ¥2500

S1P-H5110-1mg (500ug x 2) / ¥13000

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