ClinMax™ Human TNF-α Quantitative ELISA Kit is designed to quantitate human TNF-α that is present in complex biological matrices, such as human serum, plasma, buffered solution, or cell culture. Tumor necrosis factor alpha (TNF-alpha), is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
This immunoassay is designed to quantitate human TNF-α that is present in human serum, plasma, buffered solution, or cell culture. It has been calibrated against a highly purified human TNF-α and is evaluated with standard from NIBSC/WHO. Reference Reagent TNF-α (Human, rDNA derived) NIBSC code: 12/154.
It is for research use only.
The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C.
The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.