Human Tau-412 / 1N4R Protein, Tag Free, low Endotoxin (MALS verified)

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Qty.
TAU-H5119-100ug
¥2940.00
TAU-H5119-1mg
¥20580.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

  • 表达区间及表达系统(Source)

    Human Tau-412 Protein, Tag Free (TAU-H5119) is expressed from E. coli cells. It contains AA Met 1 - Leu 412 (Accession # P10636-7).

    Predicted N-terminus: Met

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    Tau Structure

    This protein carries no "tag".

    The protein has a calculated MW of 43 kDa. The protein migrates as 43 kDa,45 kDa and 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • 内毒素(Endotoxin)

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    Tau SDS-PAGE

    Human Tau-412 Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Tau SEC-MALS

    The purity of Human Tau-412 Protein, Tag Free (Cat. No. TAU-H5119) is more than 90% and the molecular weight of this protein is around 35-55 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     Tau ELISA

    Immobilized Human Tau-412 Protein, Tag Free (Cat. No. TAU-H5119) at 1 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.06-8 ng/mL (QC tested).

    Protocol

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背景介绍

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

前沿进展

 
药物研发进展
  • 英文全称:

    Microtubule-associated protein tau

  • 中文全称:

    微管相关蛋白tau

  • 种类:

  • 上市药物数量:

    1 详情

  • 临床药物数量:

    38 详情

  • 最高研发阶段:

    临床三期

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