Biotinylated Domestic porcine Serum Albumin Protein, His,Avitag™ (MALS verified)

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DSA-D82E1-25ug
¥3675.00
DSA-D82E1-200ug
¥14490.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    Serum albumin, ALB, Alb

  • 表达区间及表达系统(Source)

    Biotinylated Domestic porcine Serum Albumin Protein, His,Avitag (DSA-D82E1) is expressed from human 293 cells (HEK293). It contains AA Arg 19 - Ala 607 (Accession # A2THZ2-1).

    Predicted N-terminus: Arg 19

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    Serum Albumin Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 71.1 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 标记(Labeling)

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • 蛋白标记度(Protein Ratio)

    Passed as determined by the HABA assay / binding ELISA.

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    Serum Albumin SDS-PAGE

    Biotinylated Domestic porcine Serum Albumin Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    Serum Albumin SEC-MALS

    The purity of Biotinylated Domestic porcine Serum Albumin Protein, His,Avitag (Cat. No. DSA-D82E1) is more than 85% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

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背景介绍

serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

前沿进展

 
药物研发进展
  • 英文全称:

    Serum albumin

  • 中文全称:

    血清白蛋白

  • 种类:

  • 上市药物数量:

    17 详情

  • 临床药物数量:

    13 详情

  • 最高研发阶段:

    批准上市

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