Human PADI2 Protein, His Tag, low Endotoxin (InsectCells)

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PA2-H5543-50ug
¥4200.00
PA2-H5543-1mg
¥29400.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    PADI2,PAD-H19,KIAA0994,PAD2,PDI2

  • 表达区间及表达系统(Source)

    Human PADI2, His Tag (PA2-H5543) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 665 (Accession # Q9Y2J8-1).

    Predicted N-terminus: Met

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    PADI2 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 77.4 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE).

  • 内毒素(Endotoxin)

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    PADI2 SDS-PAGE

    Human PADI2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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背景介绍

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

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