SARS-CoV-2 (COVID-19) NSP8 Protein, His Tag

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NS8-C5149-100ug
¥4200.00
NS8-C5149-1mg
¥27300.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    NSP8, nsp8, Non-structural protein 8

  • 表达区间及表达系统(Source)

    SARS-CoV-2 NSP8, His Tag (NS8-C5149) is expressed from E. coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1).

    Predicted N-terminus: Met

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    NSP8 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 23.9 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE).

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 250 mM NaCl, pH8.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    NSP8 SDS-PAGE

    SARS-CoV-2 NSP8, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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背景介绍

NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.

前沿进展

 
药物研发进展
  • 英文全称:

    SARS-CoV-2-3C-like-proteinase

  • 中文全称:

    SARS冠状病毒2-3C样蛋白酶

  • 种类:

  • 上市药物数量:

    5 详情

  • 临床药物数量:

    29 详情

  • 最高研发阶段:

    批准上市

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