Human LILRB5 / CD85c / LIR-8 Protein, His Tag

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价格
Qty.
CDC-H5220-100ug
¥4045.00
CDC-H5220-1mg (100ug X 10)
¥24150.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    LILRB5,CD85c,LIR-8

  • 表达区间及表达系统(Source)

    Human LILRB5, His Tag (CDC-H5220) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 458 (Accession # NP_006831).

    Predicted N-terminus: Gly 24

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    LILRB5 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 49.2 kDa. The protein migrates as 66-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    LILRB5 SDS-PAGE

    Human LILRB5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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背景介绍

Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation. Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.

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