PE-Labeled Human LAG-3 / CD223 Protein, His TagStar Staining

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LA3-HP2H4-25tests
¥3675.00
LA3-HP2H4-200tests
¥22890.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    LAG3, CD223, FDC

  • 表达区间及表达系统(Source)

    PE-Labeled Human LAG-3 Protein, His Tag (LA3-HP2H4) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Leu 450 (Accession # P18627-1).

    Predicted N-terminus: Leu 23

  • 蛋白结构(Molecular Characterization)

    LAG-3 Structure

    This protein carries a polyhistidine tag at the C-terminus.

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, 0.2% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     LAG-3 FACS

    Flow cytometric analysis of Daudi cells staining with PE-Labeled Human LAG-3 / CD223 Protein, His TagStar Staining (Cat. No. LA3-HP2H4) at 1:10 dilution (10 μL of the antibody stock solution corresponds to labeling of 5e5 cells in a final volume of 100 µL), compared with negative control protein. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

前沿进展

 
药物研发进展
  • 英文全称:

    Lymphocyte activation gene 3 protein

  • 中文全称:

    淋巴细胞活化基因3蛋白

  • 种类:

  • 上市药物数量:

    1 详情

  • 临床药物数量:

    28 详情

  • 最高研发阶段:

    批准上市

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