Human IL-9 Protein, premium grade

用户评价
货号-规格
价格
Qty.
IL9-H5214-1mg (250ug X 4)
¥24255.00
IL9-H5214-100ug
¥3675.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    Interleukin-9,IL-9,Cytokine P40

  • 表达区间及表达系统(Source)

    Human IL-9 Protein, premium grade (IL9-H5214) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Ile 144 (Accession # P15248-1).

    Predicted N-terminus: Gln 19

    It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    IL-9 Structure

    This protein carries no "tag".

    The protein has a calculated MW of 14.1 kDa. The protein migrates as 30 kDa±3 kDa under reducing (R) condition, and 30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

  • 内毒素(Endotoxin)

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • 宿主蛋白残留(Host Cell Protein)

    <0.5 ng/µg of protein tested by ELISA.

  • 宿主核酸残留(Host Cell DNA)

    <0.02 ng/μg of protein tested by qPCR.

  • 无菌(Sterility)

    Negative

  • 支原体(Mycoplasma)

    Negative.

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 24 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

推荐产品

数据展示

  • 电泳(SDS-PAGE)

    IL-9 SDS-PAGE

    Human IL-9 Protein, premium grade on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    IL-9 SEC-MALS

    The purity of Human IL-9 Protein, premium grade (Cat. No. IL9-H5214) is more than 95% and the molecular weight of this protein is around 18-25 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     IL-9 ELISA

    Immobilized Human IL-9 Protein, premium grade (Cat. No. IL9-H5214) at 5 μg/mL (100 μL/well) can bind Human IL-9R, Fc Tag (Cat. No. ILR-H5251) with a linear range of 2-78 ng/mL (QC tested).

    Protocol

用户评价
发表评论

背景介绍

Interleukin-9 (IL-9) is expressed primarily by activated T cells. The growth factor and anti apoptotic activities of IL-9 on multiple transformed cells suggest a potential role for the cytokine in tumourigenesis. IL-9 has also been proposed as a candidate gene for asthma IL-9 is a Th2-derived cyto kine that has been reported to regulate T and B cell function. IL-9was first isolated as a factor capable of sustaining the long-termgrowth of murine T cell clones, but has since been demon strated to have in vitro activities on mast cells, erythroid pro genitors, and B cell Ig expression.

前沿进展

 
药物研发进展
  • 英文全称:

    Interleukin-9

  • 中文全称:

    白细胞介素-9

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    2 详情

  • 最高研发阶段:

    临床二期

联系我们
项目合作
查看更多项目
实验案例分析
查看更多案例分析
  • 产品基础信息
  • 产品详情
  • 推荐产品
  • 数据展示
  • 用户评价
  • 背景介绍