FITC-Labeled Human IL-3 R alpha / CD123 Protein, His Tag

用户评价
货号-规格
价格
Qty.
ILA-HF2H9-25ug
¥3350.00
ILA-HF2H9-200ug
¥20790.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha

  • 表达区间及表达系统(Source)

    FITC-Labeled Human IL-3 R alpha, His Tag (ILA-HF2H9) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1). It is the FITC labeled form of Human IL-3 R alpha, His Tag (Cat. No. ILA-H52H6).

    Predicted N-terminus: Thr 19

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    IL-3 R alpha Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 35.0 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    FITC

    Excitation source: 488 nm spectral line, argon-ion laser

    Excitation Wavelength: 488 nm

    Emission Wavelength: 535 nm

  • 标记(Labeling)

    The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with FITC using standard chemical labeling method. The residual FITC is removed by molecular sieve treatment during purification process.

  • 蛋白标记度(Protein Ratio)

    The FITC to protein molar ratio is 3-5.

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

推荐产品

数据展示

  • 电泳(SDS-PAGE)

    IL-3 R alpha SDS-PAGE

    FITC-Labeled Human IL-3 R alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

用户评价
发表评论

背景介绍

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

前沿进展

 
药物研发进展
  • 英文全称:

    Interleukin-3 receptor subunit alpha

  • 中文全称:

    白细胞介素-3受体α亚基

  • 种类:

  • 上市药物数量:

    1 详情

  • 临床药物数量:

    37 详情

  • 最高研发阶段:

    批准上市

联系我们
项目合作
查看更多项目
实验案例分析
查看更多案例分析
  • 产品基础信息
  • 产品详情
  • 推荐产品
  • 数据展示
  • 用户评价
  • 背景介绍