PE-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag (Site-specific conjugation)

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ILP-HP2H3-25tests
¥3520.00
ILP-HP2H3-200tests
¥22890.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    IL1RAP,IL-1RAcP,C3orf13,IL1R3

  • 表达区间及表达系统(Source)

    PE-Labeled Human IL-1 RAcP / IL-1 R3, His Tag (ILP-HP2H3) is produced via site-specific conjugation of PE to Human IL-1 RAcP / IL-1 R3 Protein, His Tag under optimal conditions with a proprietary technology. PE-Labeled Human IL-1 RAcP, His Tag (ILP-HP2H3) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3-1).

    Predicted N-terminus: Ser 21

    Request for sequence

  • 蛋白结构(Molecular Characterization)

    IL-1 RAcP Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 42.7 kDa.

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 应用说明(Application)

    Please note that this product is NOT compatible to streptavidin detection system.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, 0.5%BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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背景介绍

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

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药物研发进展
  • 英文全称:

    Interleukin-1 receptor accessory protein

  • 中文全称:

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    4 详情

  • 最高研发阶段:

    临床二期

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