Human HSP90AA1 / HSP86 Protein, GST Tag

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HS1-H513x-100ug
¥2625.00
HS1-H513x-1mg
¥16800.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    HSP90AA1, HSP90A, HSP 86, HSP86, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2

  • 表达区间及表达系统(Source)

    Human HSP90AA1, GST Tag (HS1-H513x) is expressed from E. coli cells. It contains AA Glu 535 - Asp 732 (Accession # NP_005339).

    Predicted N-terminus: Met

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    HSP90AA1 Structure

    This protein carries a GST tag at the N-terminus.

    The protein has a calculated MW of 49.3 kDa. The protein migrates as 27 kDa,29 kDa,31-32 kDa and 47-49 kDa under reducing (R) condition (SDS-PAGE).

  • 纯度(Purity)

    >85% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in 50 mM HEPES, 150 mM NaCl, pH7.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    HSP90AA1 SDS-PAGE

    Human HSP90AA1, GST Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 85%.

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背景介绍

Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

前沿进展

 
药物研发进展
  • 英文全称:

    Heat shock protein HSP 90-alpha

  • 中文全称:

    热休克蛋白90α家族A类成员1

  • 种类:

  • 上市药物数量:

    1 详情

  • 临床药物数量:

    0 详情

  • 最高研发阶段:

    批准上市

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