Human DRD1 Full Length Protein (VLP)

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货号-规格
价格
Qty.
DR1-H52P6-20ug
¥6300.00
DR1-H52P6-100ug
¥12600.00
DR1-H52P6-500ug (250ug X 2)
¥39900.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    DRD1, Dopamine D1 receptor, D1R; DADR; DRD1A

  • 表达区间及表达系统(Source)

    Human DRD1 Full Length Protein (VLP) (DR1-H52P6) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Thr 446 (Accession # P21728-1).

  • 蛋白结构(Molecular Characterization)

    Virus-like particles(VLPs) are formed by self-assembly of capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.

    The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • 制剂(Formulation)

    The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

    Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程
  • *The isotype control of empty/mock VLP (Cat. No. VLP-N5213) is sold separately and not included in protein, you can follow this link for product information.

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  • 活性(Bioactivity)-ELISA

     DRD1 ELISA

    Immobilized Human DRD1 Full Length Protein (VLP) (Cat. No. DR1-H52P6) at 2 μg/mL (100 μL/well) can bind Anti-DAD1 Polyclonal antibody, Rabbit IgG with a linear range of 0.5-31 ng/mL (QC tested).

    Protocol

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背景介绍

The dopamine receptor D1 (Drd1) is a member of the D1-like receptor family and is the most abundant dopamine receptor in the central nervous system. The receptor is found in the cortex, striatum and limbic system of the brain and the cardiovascular system.

前沿进展

 
药物研发进展
  • 英文全称:

    Dopamine D1 receptor

  • 中文全称:

    多巴胺D1受体

  • 种类:

  • 上市药物数量:

    8 详情

  • 临床药物数量:

    16 详情

  • 最高研发阶段:

    批准上市

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