产品详情
分子别名(Synonym)
BONZO, CD186, CDw186, STRL34, TYMSTR, C-X-C motif chemokine receptor 6
表达区间及表达系统(Source)
Fluorescent Human CXCR6 Full Length Protein (VLP) (CX6-H52G3) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Leu 342 (Accession # O00574-1).
Predicted N-terminus: Asp
蛋白结构(Molecular Characterization)
This protein carries a GFP tag at the C-terminus.
Virus-like particles(VLPs) are formed by self-assembly of capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.
偶联(Conjugate)
GFP
Excitation source: 488 nm spectral line, argon-ion laser
Excitation Wavelength: 488 nm
Emission Wavelength: 530 nm
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method / rFC method.
制剂(Formulation)
The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).
Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
运输(Shipping)
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存储(Storage)
Please protect from light and avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 12 months under sterile conditions.
质量管理控制体系(QMS)
- *The isotype control of empty/mock VLP (Cat. No. VLP-NF2P4) is sold separately and not included in protein, you can follow the link for product information.
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数据展示
活性(Bioactivity)-ELISA

Immobilized Fluorescent Human CXCR6 Full Length Protein (VLP) (Cat. No. CX6-H52G3) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CXCR6 antibody, Mouse IgG with a linear range of 0.1-6 ng/mL (QC tested).
Protocol
均一性(Identity)-DLS

The mean peak Radius of VLP is 60-80 nm with more than 95% intensity as determined by dynamic light scattering (DLS).
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