Human CXCL10 Protein, Tag Free

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CX0-H5113-50ug
¥3500.00
CX0-H5113-1mg
¥26000.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10, CXCL10(1-73), CXCL10, INP10, SCYB10

  • 表达区间及表达系统(Source)

    Human CXCL10 Protein, Tag Free (CX0-H5113) is expressed from E. coli cells. It contains AA Val 22 - Pro 98 (Accession # P02778-1 ).

    Predicted N-terminus: Met

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    CXCL10 Structure

    This protein carries no "tag".

    The protein has a calculated MW of 8.8 kDa. The protein migrates as 9 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    CXCL10 SDS-PAGE

    Human CXCL10 Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • 活性(Bioactivity)-ELISA

     CXCL10 ELISA

    Immobilized Human CXCL10 Protein, Tag Free (Cat. No. CX0-H5113) at 5 μg/mL (100 μL/well) can bind Human CXCR3 Protein, Flag,His Tag (Cat. No. CX3-H52D5) with a linear range of 0.039-10 μg/mL (QC tested).

    Protocol

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背景介绍

C-X-C Motif Chemokine Ligand 10 (CXCL10) is a pro-inflammatory chemokine secreted by a wide spectrum of cells. It is involved in multiple mechanisms and reported to have pleiotropic effects, including immune cell migration and attraction to inflammation sites, angiogenesis, and cancer cell growth. CXCL10 is produced by pancreatic islet cells upon inflammatory stress and is specifically recognized by C-X-C Motif Chemokine Receptor 3 (CXCR3) which is expressed by activated T-lymphocytes and other immune cells.

前沿进展

 
药物研发进展
  • 英文全称:

    C-X-C motif chemokine ligand 10

  • 中文全称:

    C-X-C基序趋化因子配体10

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    2 详情

  • 最高研发阶段:

    临床二期

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