Cynomolgus CEACAM-5 / CD66e Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)

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CE5-C5257-100ug
¥3675.00
CE5-C5257-1mg (500ug X 2)
¥24255.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    CEACAM-5,CD66e,CEA,Meconium antigen 100

  • 表达区间及表达系统(Source)

    Cynomolgus CEACAM-5 Protein, Llama IgG2b Fc Tag (CE5-C5257) is expressed from human 293 cells (HEK293). It contains AA Pro 593 - Ser 675 (Accession # XP_005589491.2).

    Predicted N-terminus: Pro 593

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    CEACAM-5 Structure

    This protein carries a llama IgG2b Fc tag at the C-terminus.

    The protein has a calculated MW of 36.8 kDa. The protein migrates as 53-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 内毒素(Endotoxin)

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    CEACAM-5 SDS-PAGE

    Cynomolgus CEACAM-5 Protein, Llama IgG2b Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    CEACAM-5 SEC-MALS

    The purity of Cynomolgus CEACAM-5 Protein, Llama IgG2b Fc Tag (Cat. No. CE5-C5257) is more than 95% and the molecular weight of this protein is around 90-110 kDa verified by SEC-MALS.

    Report

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背景介绍

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

前沿进展

 
药物研发进展
  • 英文全称:

    Carcinoembryonic antigen related cell adhesion molecule 5

  • 中文全称:

    癌胚抗原相关细胞粘附分子5

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    11 详情

  • 最高研发阶段:

    临床三期

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