Mouse CD23 / Fc epsilon RII Protein, His Tag (MALS verified)

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CD3-M5243-100ug
¥2940.00
CD3-M5243-1mg
¥18900.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    FCER2,CD23,CD23A,CLEC4J,FCE2,IGEBF,FcεRII,FcεRⅡ

  • 表达区间及表达系统(Source)

    Mouse CD23 Protein, His Tag (CD3-M5243) is expressed from human 293 cells (HEK293). It contains AA Glu 50 - Pro 331 (Accession # P20693.1).

    Predicted N-terminus: His

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    CD23 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 33.8 kDa. The protein migrates as 40-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    CD23 SDS-PAGE

    Mouse CD23 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    CD23 SEC-MALS

    The purity of Mouse CD23 Protein, His Tag (Cat. No. CD3-M5243) is more than 90% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

    Report

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背景介绍

Cluster of differentiation 23 (CD23) is also known as Low affinity immunoglobulin epsilon Fc receptor (FCER2), C-type lectin domain family 4 member J (CLEC4J), Fc-epsilon-RII (FcεRII), Immunoglobulin E-binding factor (IGEBF), is the 'low-affinity' receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

前沿进展

 
药物研发进展
  • 英文全称:

    Immunoglobulin epsilon Fc receptor

  • 中文全称:

    免疫球蛋白ε-Fc受体

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    2 详情

  • 最高研发阶段:

    临床二期

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