Human CCL5/RANTES Protein, Tag Free

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价格
Qty.
CC5-H5113-20ug
¥1890.00
CC5-H5113-50ug
¥3780.00
CC5-H5113-1mg (200ug X 5)
¥31500.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    EoCP, Eosinophil chemotactic cytokine, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, D17S136E, SCYA5, CCL5, C-C motif chemokine 5 T-cell-specific protein RANTES

  • 表达区间及表达系统(Source)

    Human CCL5/RANTES Protein, Tag Free (CC5-H5113) is expressed from E. coli cells. It contains AA Ser 24 - Ser 91 (Accession # P13501-1).

    Predicted N-terminus: Ser 24

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    CCL5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 7.9 kDa. The protein migrates as 8-9 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    CCL5 SDS-PAGE

    Human CCL5/RANTES Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • 活性(Bioactivity)-ELISA

     CCL5 ELISA

    Immobilized Human CCL5/RANTES Protein, Tag Free (Cat. No. CC5-H5113) at 5 μg/mL (100 μL/well) can bind Human CCR2 Full Length Protein, Flag,His Tag (Cat. No. CC2-H52D4) with a linear range of 0.005-0.313 μg/mL (QC tested).

    Protocol
  •  CCL5 ELISA

    Immobilized Human CCL5/RANTES Protein, Tag Free (Cat. No. CC5-H5113) at 5 μg/mL (100 μL/well) can bind Human CCR5, Flag,His Tag (Cat. No. CC5-H52D1) with a linear range of 0.005-0.313 μg/mL (Routinely tested).

    Protocol

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背景介绍

C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.

前沿进展

 
药物研发进展
  • 英文全称:

    C-C motif chemokine 5

  • 中文全称:

    C-C基序趋化因子-5

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    2 详情

  • 最高研发阶段:

    临床二期

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