Biotinylated Cynomolgus Carbonic Anhydrase XII Protein, His,Avitag™ (active enzyme, MALS verified)

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CAI-C82E3-20ug
¥3150.00
CAI-C82E3-100ug
¥9240.00
CAI-C82E3-500ug (250ug X 2)
¥31500.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    Carbonic Anhydrase XII,CA XII,Car12,CA-XII,Carbonate dehydratase XII

  • 表达区间及表达系统(Source)

    Biotinylated Cynomolgus Carbonic Anhydrase XII Protein, His,Avitag (CAI-C82E3) is expressed from human 293 cells (HEK293). It contains AA Ala 25 - Gly 299 (Accession # A0A2K5TSB2-1).

    Predicted N-terminus: Ala 25

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    Carbonic Anhydrase XII Structure

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 34.5 kDa. The protein migrates as 42-52 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 标记(Labeling)

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • 蛋白标记度(Protein Ratio)

    Passed as determined by the HABA assay / binding ELISA.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in 50mM Tris,150mM NaCl,PH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    Carbonic Anhydrase XII SDS-PAGE

    Biotinylated Cynomolgus Carbonic Anhydrase XII Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    Carbonic Anhydrase XII SEC-MALS

    The purity of Biotinylated Cynomolgus Carbonic Anhydrase XII Protein, His,Avitag (Cat. No. CAI-C82E3) is more than 95% and the molecular weight of this protein is around 45-60 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)

    Measured by its esterase activity. The specific activity is >10 pmol/min/μg (QC tested).

    Protocol

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背景介绍

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.

前沿进展

 
药物研发进展
  • 英文全称:

    Carbonic anhydrase XII

  • 中文全称:

    碳酸酐酶XII

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    1 详情

  • 最高研发阶段:

    临床一期

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