Human BTN3A1 / CD277 Protein, His Tag, active dimer (MALS verified)

用户评价
货号-规格
价格
Qty.
BT1-H52H4-100ug
¥3650.00
BT1-H52H4-1mg (500ug X 2)
¥21830.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    BTN3A1,CD277,BTF5

  • 表达区间及表达系统(Source)

    Human BTN3A1 Protein, His Tag (BT1-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Gly 254 (Accession # O00481-1).

    Predicted N-terminus: Gln 30

  • 蛋白结构(Molecular Characterization)

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 29.5 kDa. The protein migrates as 32-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

推荐产品

数据展示

  • 电泳(SDS-PAGE)

    BTN3A1 SDS-PAGE

    Human BTN3A1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    BTN3A1 SEC-MALS

    The purity of Human BTN3A1 Protein, His Tag (Cat. No. BT1-H52H4) is more than 85% and the molecular weight of this protein is around 65-80 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     BTN3A1 ELISA

    Immobilized Human BTN3A1 Protein, His Tag (Cat. No. BT1-H52H4) at 1 μg/mL (100 μL/well) can bind Human BTN3A1/2/3 Antibody with a linear range of 0.1-3 ng/mL (QC tested).

    Protocol

用户评价
发表评论

背景介绍

Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

前沿进展

 
药物研发进展
  • 英文全称:

    Butyrophilin subfamily 3 member A1

  • 中文全称:

    嗜乳脂蛋白家族亚型3成员A1

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    1 详情

  • 最高研发阶段:

    临床二期

联系我们
项目合作
查看更多项目
实验案例分析
查看更多案例分析
  • 产品基础信息
  • 产品详情
  • 推荐产品
  • 数据展示
  • 用户评价
  • 背景介绍