Human ANGPTL7 / CDT6 Protein, His Tag

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AN7-H52H3-100ug
¥4305.00
AN7-H52H3-1mg
¥28350.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    ANGPTL7,CDT6

  • 表达区间及表达系统(Source)

    Human ANGPTL7 Protein, His Tag (AN7-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Pro 346 (Accession # O43827-1).

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    ANGPTL7 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 39.0 kDa. The protein migrates as 48-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    ANGPTL7 SDS-PAGE

    Human ANGPTL7 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • 活性(Bioactivity)-SPR

     ANGPTL7 SPR

    Cynomolgus LILRB4, His Tag (Cat. No. CDK-C5227) immobilized on CM5 Chip can bind Human ANGPTL7 Protein, His Tag (Cat. No. AN7-H52H3) with an affinity constant of 0.792 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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背景介绍

Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

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