Unconjugated Human FcR Protein Panel

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货号-规格
价格
Qty.
FCR-A001-450ug
¥12697.00
合计0件 产品金额¥ 0

产品详情

  • 组分(Components)

    Cat. No.
    Name
    Size
    FCN-H52W7
    Human FCGRT&B2M Heterodimer Protein
    50 μg
    FCA-H52H1
    Human CD64 Protein, His Tag
    50 μg
    CDA-H5221
    Human CD32a (R167) Protein, His Tag
    50 μg
    CD1-H5223
    Human CD32a (H167) Protein, His Tag
    50 μg
    CDB-H5228
    Human CD32b/c Protein, His Tag
    50 μg
    CD8-H52H4
    Human CD16a (V176) Protein, His Tag
    50 μg
    CDA-H5220
    Human CD16a (F176) Protein, His Tag
    50 μg
    CDB-H5227
    Human CD16b (NA1) Protein, His Tag
    50 μg
    CDB-H5222
    Human CD16b (NA2) Protein, His Tag
    50 μg
  • 产品参数(Key parameter)

    Purity (SDS PAGE)
    > 95%
    Purity (MALS)
    90%
  • 优势特色(Features)

    Comprehensive FcRs Protein Panel – No separate purchasing needed

    High Purity – >95% by SDS-PAGE; >90% by SEC-MALS

    Robust Stability – High batch-to-batch consistency

    Full Data Package – SPR, BLI, and ELISA activity data included

  • 纯度(Purity)

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

    • 活性(Bioactivity)-SPR

       - SPR

      Captured Human FCGRT&B2M Heterodimer Protein, His Tag (Cat. No. FCN-H52W7) on CM5 Chip via Anti-His antibody can bind Herceptin® (Trastuzumab) with an affinity constant of 0.516 μM as determined in a SPR assay (Biacore T200) (QC tested).

      Protocol
    •  - SPR

      Human CD64, His Tag (Cat. No. FCA-H52H1) captured on CM5 chip via anti-His antibody can bind Herceptin® with an affinity constant of 4.92 nM as determined in a SPR assay (Biacore 8K) (QC tested).

      Protocol
    •  - SPR

      Rituximab biosimilar (Cat. No. CD0-M36) captured on Protein A Chip can bind Human CD32a (R167), His Tag (Cat. No. CDA-H5221) with an affinity constant of 1.05 μM as determined in a SPR assay (Biacore 8K) (QC tested).

      Protocol
    •  - SPR

      Immobilized Human CD32a (H167), His Tag (SPR & BLI verified) (Cat. No. CD1-H5223) on CM5 Chip via anti-His antibody, can bind Rituximab with an affinity constant of 1.45 μM as determined in a SPR assay (Biacore T200) (QC tested).

      Protocol
    •  - SPR

      Immobilized Human CD32b/c, His Tag (Cat. No. CDB-H5228) on CM5 Chip via anti-His antibody, can bind Rituximab with an affinity constant of 15.1 μM as determined in a SPR assay (Biacore T200) (QC tested).

      Protocol
    •  - SPR

      Immobilized Human CD16a (V176), His Tag (Cat. No. CD8-H52H4) on CM5 Chip via anti-His antibody, can bind Herceptin with an affinity constant of 0.463 μM as determined in SPR assay (Biacore T200) (QC tested).

      Protocol
    •  - SPR

      Human CD16a (F176), His Tag (Cat. No. CDA-H5220) captured on CM5 chip via anti-His antibody can bind Rituximab biosimilar (Cat. No. CD0-M36) with an affinity constant of 1.18 µM as determined in a SPR assay (Biacore 8K) (QC tested).

      Protocol
    •  - SPR

      Immobilized Human CD16b (NA1), His Tag (Cat. No. CDB-H5227) on CM5 Chip via anti-His antibody, can bind Rituximab with an affinity constant of 8.17 μM as determined in a SPR assay (Biacore T200) (QC tested).

      Protocol
    •  - SPR

      Immobilized Human CD16b (NA2), His Tag (Cat. No. CDB-H5222) on CM5 Chip via anti-His antibody, can bind Rituximab with an affinity constant of 2.88 μM as determined in a SPR assay (Biacore T200) (QC tested).

      Protocol

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