ActiveMax® DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm)

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货号-规格
价格
Qty.
MBS-C029-2.5mg
¥26820.00
MBS-C029-10mg (2.5mg X 4)
¥65830.00
合计0件 产品金额¥ 0

产品详情

  • Product
    Size
    Amount
    ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm)
    2.5 mg
    2.5×10⁷ beads
    ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm)
    10 mg (2.5 mg×4)
    1.0×10⁸ beads
  • 产品描述(Product Description)

    ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm) are uniform, superparamagnetic beads of 5.5 µm coated with an optimized mixture of human VCAM-1/CD106 protein (premium grade) and human DLL4 protein (premium grade). They were expressed from human 293 cells (HEK293). Human VCAM-1 / CD106 protein contains AA Phe 25 - Glu 698 (Accession # P19320-1), and human DLL4 protein contains AA Ser 27 - Pro 524 ((Accession # NP_061947.1).
    ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm) are produced under sterile manufacturing conditions (ISO 5), and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

  • 应用说明(Application)

    ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm) is designed to synergistically activate Notch signaling in hematopoietic stem/progenitor cells (HSPCs). The synergistic interactions between Notch ligand Delta-like 4 and VCAM-1 are leveraged to enhance Notch signaling to support efficient T-cell lineage commitment, so the beads are recommended to use for in vitro production of induced pluripotent stem cell derived T cells.

  • 重构方法(Reconstitution)

    See Certificate of Analysis (CoA) for detailed instruction.

  • 存储(Storage)

    This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.

    Please avoid repeated freeze-thaw cycles after reconstitution. Immediate use after reconstitution is highly recommended.

  • 无菌(Sterility)

    Negative

  • 内毒素(Endotoxin)

    Less than 0.002 EU per μg by the LAL method / rFC method.

  • 支原体(Mycoplasma)

    Negative

  • 注意事项(Important Note)

    This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

  • 制剂(Formulation)

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 流式数据 -FACS Data

     DLL4 FACS

    Assay of proteins on ActiveMax® Human DLL4 / VCAM-1 μBeads surface by Flow cytometry. The human VCAM-1 / CD106 protein and human DLL4 protein conjugated on the μBeads surface were fluorescently stained using APC anti-human DLL4 antibody and then analyzed by flow cytometry (QC tested).

    Protocol
  •  DLL4 FACS

    Assay of proteins on ActiveMax® Human DLL4 / VCAM-1 μBeads surface by Flow cytometry. The human VCAM-1 / CD106 protein and human DLL4 protein conjugated on the μBeads surface were fluorescently stained using PE anti-human CD106 antibody and then analyzed by flow cytometry (QC tested).

    Protocol

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前沿进展

 
药物研发进展
  • 英文全称:

    Delta-like protein 4

  • 中文全称:

    δ样蛋白-4

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    3 详情

  • 最高研发阶段:

    临床三期

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