Recombinant Monoclonal Anti-PD-L1 Antibody, Rabbit (5D3)

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货号-规格
价格
Qty.
HCS-S240-20ul
¥1280.00
HCS-S240-100ul
¥4450.00
合计0件 产品金额¥ 0

产品详情

  • 描述/背景(Background)

    Recombinant Monoclonal Anti-PD-L1 Antibody, Rabbit (5D3) is a PD-L1 primary antibody for IHC application. PD-L1, is a ligand that binds with the receptor PD1, commonly found on T-cells, and acts to block T-cell activation. PD1 expression has been observed in a variety of cancers including melanoma and non-small cell lung cancer. The interaction of PD1/PDL1 is hypothesized to be a possible mechanism for the tumor to escape immune response. A number of checkpoint blockade inhibitors including pembrolizumab and nivolumab have been developed that target the PD1/PDL1 interaction in order to allow T-cells to recognize tumor cells without being deactivated by the tumor.

  • 产品参数(Product Specifications)

    Host Species
    Rabbit
    Isotype
    IgG
    Clone
    5D3
    Application
    IHC
    Property
    1:1000
    State
    Liquid
    Positive Control
    Human Tonsil Tissues
    Clonality
    Monoclonal
    Research Field
    Cancer Drug Targets
    Source
    Rabbit
    Synonym
    CD274, PD-L1
  • 操作步骤(Experiment Protocol)

    LEICA手工染色操作步骤

  • 储存(Storage)

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. The shelf life is 30 days from the date of opening.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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典型数据(Typical Data)
  • 质控样本(Control Sample)

     PD-L1 CONTROL SAMPLE

    Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HCS-S240 at 1/1000 dilution.
    Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • 肿瘤样本(Cancer Sample)

     PD-L1 CANCER SAMPLE
     PD-L1 CANCER SAMPLE
     PD-L1 CANCER SAMPLE

    Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HCS-S240 at 1/1000 dilution.
    Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

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前沿进展

 
药物研发进展
  • 英文全称:

    Programmed death-ligand 1

  • 中文全称:

    程序性死亡配体1

  • 种类:

  • 上市药物数量:

    11 详情

  • 临床药物数量:

    152 详情

  • 最高研发阶段:

    批准上市

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