PE-Labeled Monoclonal Anti-Human NKp46 Antibody, Mouse IgG1 (4E5) (0.03% Proclin)

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货号-规格
价格
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FABm041-01-200tests (50tests X 4)
¥2000.00
合计0件 产品金额¥ 0

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-Human NKp46 Antibody, Mouse IgG1 (4E5) is a mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.

  • 应用(Application)

    Flow Cytometry (Detection the expression of NKp46 on Human cells).

  • 克隆号(Clone)

    4E5

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG1 | Mouse kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with NKp46 protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human NKp46 Protein

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 同型对照(Isotype Control)

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM1 for product information.

  • 推荐稀释比(Recommended Dilution)

    1:20

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.03% Proclin300, 0.2% BSA with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储(Storage)

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • 运输(Shipping)

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     NKp46 FACS

    Flow cytometric analysis of HEK293/Human NKp46 Stable cells staining with PE-Labeled Monoclonal Anti-Human NKp46 Antibody, Mouse IgG1 (4E5) (Cat. No. FABm041-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

前沿进展

 
药物研发进展
  • 英文全称:

    Natural cytotoxicity triggering receptor 1

  • 中文全称:

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    4 详情

  • 最高研发阶段:

    临床二期

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