Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) (MALS verified)

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RSV-MY2231-100ug
¥3150.00
RSV-MY2231-1mg (500ug X 2)
¥18900.00
合计0件 产品金额¥ 0

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • 克隆号(Clone)

    8E6

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Human IgG1 | Human Kappa

  • 偶联(Conjugate)

    Unconjugated

  • 抗体类型(Antibody Type)

    Recombinant Monoclonal

  • 种属反应性(Reactivity)

    Virus

  • 免疫原(Immunogen)

    Recombinant HRSV (A) Glycoprotein G Protein is expressed from human 293 cells.

  • 特异性(Specificity)

    Specific recognition of HRSV (A) Glycoprotein G Protein.

  • 应用(Application)

    Application
    Recommended Usage
    ELISA
    0.06-125 ng/mL
  • 纯度(Purity)

    95% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • 纯化(Purification)

    Protein A purified / Protein G purified

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 交叉验证(Cross Verification)

    This product No cross-reactivity in ELISA with

    HRSV (A) Glycoprotein G Protein, His Tag (Cat. No. GLG-V5143).

    HRSV (B) Glycoprotein G Protein, His Tag (Cat. No. GLG-V5144).

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    HRSV Glycoprotein (RSV-G) SDS-PAGE

    Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    HRSV Glycoprotein (RSV-G) SEC-MALS

    The purity of Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) (Cat. No. RSV-MY2231) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     HRSV Glycoprotein (RSV-G) ELISA

    Immobilized HRSV (A) Glycoprotein G Protein, His Tag (Cat. No. RSG-V5221) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) (Cat. No. RSV-MY2231) with a linear range of 0.06-2 ng/mL (QC tested).

    Protocol

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背景介绍

The two major glycoproteins on the surface of the RSV virion, the attachment glycoprotein (G) and the fusion (F) glycoprotein, control the initial phases of infection. The central region of the G protein contains a 13-amino acid highly conserved domain, partially overlapping the cysteine noose domain with 4 cysteines linked 1–4 and 2–3, followed by a highly basic heparin-binding domain (HBD). The HBD is the likely attachment site for heparan sulfate (HS) found on the surface of most cells. A peptide from the G protein HBD (amino acids 184–198) binds efficiently to HEp-2 cells and inhibits RSV infection.

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