PE-Labeled Monoclonal Anti-Human CD69 Antibody, Mouse IgG1 (3C5B7) (0.03% Proclin)

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货号-规格
价格
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FABm022-01-50tests
¥700.00
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产品详情

  • 抗体来源(Source)

    PE-Labeled Monoclonal Anti-Human CD69 Antibody, Mouse IgG1 (3C5B7) is a mouse monoclonal antibody recombinantly expressed from Hybridoma.

  • 应用(Application)

    Flow Cytometry (Evaluation of the expression of CD69 on Human cells).

  • 克隆号(Clone)

    3C5B7

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG1 | Mouse Kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with CD69 protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human CD69 Protein.

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 同型对照(Isotype Control)

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM1 for product information.

  • 推荐稀释比(Recommended Dilution)

    1:20

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储(Storage)

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     CD69 FACS

    Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD69 Antibody, Mouse IgG1 (3C5B7) (Cat. No. FABm022-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

The activation of T lymphocytes involves a wide variety of cellular changes. Some of these changes are biochemical in nature, such as phosphatidylinositol catabolism and the elevationof cellular calcium. Others are genetic, involving the induction of specific gene expression. Among the constellation of genes induced following T cell activation are several cell surface molecules. One of the earliest of these to be expressed is CD69 (previously known as activation inducer molecule or AIM, EA-1, Leu-23,and MLR3). Within one to two h of activation, CD69 can be found on the cell surface, with expression persisting at least three days. Studies with monoclonal antibodies (MAb) to CD69 have shown that it is a costimulatory molecule for T cell proliferation. In addition, CD69 expression can be induced on most, if not all, cells of hematopoietic origin.

前沿进展

 
药物研发进展
  • 英文全称:

    DNA (cytosine-5)-methyltransferase 1

  • 中文全称:

    DNA(胞嘧啶-5)-甲基转移酶-1

  • 种类:

  • 上市药物数量:

    5 详情

  • 临床药物数量:

    9 详情

  • 最高研发阶段:

    批准上市

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