PE-Labeled Monoclonal Anti-Human CD45RO Antibody, Mouse IgG2a (UCHL1) (0.03% Proclin)

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货号-规格
价格
Qty.
FABm021-01-50tests
¥700.00
合计0件 产品金额¥ 0

产品详情

  • 应用(Application)

    Flow Cytometry (Evaluation of the expression of CD45RO on Human cells).

  • 克隆号(Clone)

    UCHL1

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG2a | Mouse Kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with CD45RO protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human CD45RO Protein.

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 同型对照(Isotype Control)

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM487 for product information.

  • 推荐稀释比(Recommended Dilution)

    1:20

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储(Storage)

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     CD45RO FACS

    Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD45RO Antibody, Mouse IgG2a (UCHL1) (Cat. No. FABm021-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol
  • Compared Data

     CD45RO COMPARED_DATA

    Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD45RO Antibody. PE signal was used to evaluate the binding activity of Anti-Human CD45RO Antibody. The biological activity level of ACRO is superior to competitor BL (Routinely tested).

    Protocol

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背景介绍

CD45 is a glycoprotein with protein phosphatase activity abundantly expressed on the surface of all leukocytes. The protein is highly preserved during evolution and has been demonstrated even in chicken, sharks, and mosquitos. CD45 increases T-cell and B-cell receptor signaling as well as the development and function of leukocytes. Moreover, CD45 can reduce Toll-like receptors and cytokine signaling, as well as cell adhesion and migration in a cell type specific manner. In humans, six splice variants differing in the extracellular part of the molecule have been demonstrated. The human variants are termed CD45RABC (also named CD45R), CD45RAB, CD45RBC, CD45RA, CD45RB, and CD45RO, and are detected by subtype specific antibodies and molecular weight, respectively. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells.

前沿进展

 
药物研发进展
  • 英文全称:

    Leukocyte common antigen

  • 中文全称:

    白细胞共同抗原

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    3 详情

  • 最高研发阶段:

    临床三期

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