PE-Labeled Monoclonal Anti-Human CD45RA Antibody, Mouse IgG2b (AS624) (0.03% Proclin)

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货号-规格
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FABm040-01-200tests (50tests X 4)
¥2000.00
合计0件 产品金额¥ 0

产品详情

  • 应用(Application)

    Flow Cytometry (Evaluation of the expression of CD45RA on Human cells).

  • 克隆号(Clone)

    AS624

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG2b | Mouse kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with CD45RA protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human CD45RA Protein

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 同型对照(Isotype Control)

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM486 for product information.

  • 推荐稀释比(Recommended Dilution)

    1:20

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.03% Proclin300, 0.2% BSA with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储(Storage)

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • 运输(Shipping)

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     CD45RA FACS

    Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD45RA Antibody, Mouse IgG2b (AS624) (Cat. No. FABm040-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

前沿进展

 
药物研发进展
  • 英文全称:

    Leukocyte common antigen

  • 中文全称:

    白细胞共同抗原

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    3 详情

  • 最高研发阶段:

    临床三期

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