APC-Labeled Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10) (0.03% Proclin)

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Qty.
CD2-AHFM8-25tests
¥1600.00
CD2-AHFM8-200tests
¥3600.00
合计0件 产品金额¥ 0

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10) is a mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.

  • 应用(Application)

    Flow Cytometry (Evaluation of the expression of CD2 on Human cells).

  • 克隆号(Clone)

    RPA-2.10

  • 亚型(Isotype)

    Mouse IgG1 | Mouse Kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with CD19 protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human CD2 Protein

  • 偶联(Conjugate)

    APC

    Excitation Wavelength: 640 nm

    Emission Wavelength: 661 nm

  • 推荐稀释比(Recommended Dilution)

    1:50

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin 300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 24 months in lyophilized state;
    2. -70°C for 12 months after reconstitution.
    3. 2-8 °C for 12 months after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 活性(Bioactivity)-FACS

     CD2 FACS

    Flow cytometric analysis of Human peripheral blood lymphocytes staining with APC-Labeled Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10) (Cat. No. CD2-AHFM8) at 1:50 dilution (2 μL of the antibody stock solution corresponds to labeling of 1e6 PBMCs in a final volume of 100 µL), compared with APC Mouse IgG1, κ Isotype Ctrl Antibody. APC signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.

前沿进展

 
药物研发进展
  • 英文全称:

    T-cell surface antigen CD2

  • 中文全称:

    T细胞表面抗原CD2

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    3 详情

  • 最高研发阶段:

    临床二期

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