PE-Labeled Monoclonal Anti-Human CD197 / CCR7 Antibody, Mouse IgG2a (AS651) (0.03% Proclin)

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FABm057-01-100tests (50tests X 2)
¥2100.00
合计0件 产品金额¥ 0

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-Human CD197 / CCR7 Antibody, Mouse IgG2a (AS651) is a mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.

  • 应用(Application)

    Flow Cytometry (Evaluation of the expression of CD197 / CCR7 on Human cells).

  • 克隆号(Clone)

    AS651

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG2a | Mouse Kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with CD197 / CCR7 protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human CD197 / CCR7 Protein

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 同型对照(Isotype Control)

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM487 for product information.

  • 推荐稀释比(Recommended Dilution)

    1:20

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.03% Proclin300, 0.2% BSA with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储(Storage)

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • 运输(Shipping)

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     CD197 FACS

    Flow cytometric analysis of CCR7-HEK293T cells staining with PE-Labeled Monoclonal Anti-Human CD197 Antibody, Mouse IgG2a (AS651) (Cat. No. FABm057-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

The anti-Human CD197 (CCR7) monoclonal antibody specifically binds to cell-surface CCR7 (CD197), a seven-transmembrane G-protein-coupled receptor that interacts with chemokines CCL19 and CCL21. CCR7 mediates leukocyte homing to secondary lymphoid tissues, and its differential expression distinguishes T cell subsets. Aberrant CCR7 expression is linked to lymphoma metastasis and autoimmune disease progression, making it a key target for immunotherapy research. PE-labeled CCR7 antibody can facilitate relevant drug research and development.

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