Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (MALS verified)

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货号-规格
价格
Qty.
CC8-MY2406-20ug
¥1200.00
CC8-MY2406-100ug
¥3600.00
合计0件 产品金额¥ 0

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

  • 克隆号(Clone)

    11C4C1

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG2a | Mouse Kappa

  • 偶联(Conjugate)

    Unconjugated

  • 抗体类型(Antibody Type)

    Recombinant Monoclonal

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    mRNA-CCR8

  • 特异性(Specificity)

    Specifically recognizes Human CCR8 Protein.

  • 应用(Application)

    Application
    Recommended Usage
    ELISA
    0.08-40 ng/mL
  • 纯度(Purity)

    95% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • 纯化(Purification)

    Protein A purified / Protein G purified

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 12 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 电泳(SDS-PAGE)

    CCR8 SDS-PAGE

    Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    CCR8 SEC-MALS

    The purity of Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     CCR8 ELISA

    Immobilized Human CCR8 Protein (VLP) (Cat. No. CC8-H52P5) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) with a linear range of 0.08-3 ng/mL. Virus-Like Particle (VLP) Protein Isotype Control (Cat. No. VLP-N5213) is verified not recoginized by Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) in low concentration (QC tested).

    Protocol
  • 活性(Bioactivity)-FACS

     CCR8 FACS

    1e6 of HEK293/Human CCR8 Stable Cells Line were stained with 100 μL of 1 μg/mL of Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) and isotype control antibody respectively, washed and then followed by PE anti-mouse IgG2a antibody and analyzed with FACS (QC tested).​

    Protocol

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背景介绍

CCR8 is a G protein-coupled chemokine receptor expressed on regulatory T cells and in tumor microenvironments, mediating chemotaxis, immune regulation, and pathological processes like inflammation or cancer progression. The unconjugated anti-human CCR8 antibody enables specific detection of human CCR8.

前沿进展

 
药物研发进展
  • 英文全称:

    C-C chemokine receptor type 8

  • 中文全称:

    CC趋化因子受体8型

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    14 详情

  • 最高研发阶段:

    临床二期

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