PE-Labeled Monoclonal Anti-Human BTLA Antibody, Mouse IgG2a (AS616) (0.03% Proclin)

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货号-规格
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FABm036-01-50tests
¥6000.00
合计0件 产品金额¥ 0

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-Human BTLA Antibody, Mouse IgG2a (AS616) is a mouse monoclonal antibody, which provides higher batch consistency and long term security of supply.

  • 应用(Application)

    Flow Cytometry (Evaluation of the expression of BTLA on Human cells).

  • 克隆号(Clone)

    AS616

  • 种属(Species)

    Mouse

  • 亚型(Isotype)

    Mouse IgG2a | Mouse kappa

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with BTLA protein.

  • 种属反应性(Reactivity)

    Human

  • 免疫原(Immunogen)

    Purified Human BTLA Protein

  • 偶联(Conjugate)

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • 同型对照(Isotype Control)

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM487 for product information.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.03% Proclin300, 0.2% BSA with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储(Storage)

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • 运输(Shipping)

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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数据展示

  • 活性(Bioactivity)-FACS

     BTLA FACS

    Flow cytometric analysis of THP-1 staining with PE-Labeled Monoclonal Anti-Human BTLA Antibody, Mouse IgG2a (AS616) (Cat. No. FABm036-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in afinal volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

前沿进展

 
药物研发进展
  • 英文全称:

    B- and T-lymphocyte attenuator

  • 中文全称:

    B和T淋巴细胞衰减因子

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    6 详情

  • 最高研发阶段:

    临床三期

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