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CD133信息

英文名称:CD133
中文名称:CD133抗原
靶点别称:Antigen AC133,Prominin-1,PROM1,Prominin 1,Prominin-Like Protein 1,PROML1,Stargardt Disease 4 (Autosomal Dominant),Hematopoietic Stem Cell Antigen,Macular Dystrophy, Retinal 2,Prominin (Mouse)-Like 1,CD133 Antigen,HProminin,MSTP061,CORD12,AC133,CD133,MCDR2
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

CD133产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CD3-H52H4
Human
Human CD133 Protein, His Tag
CD3-H82E6
Human
Biotinylated Human CD133 Protein, His Tag (Nanodisc)
CD3-H52H1
Human
Human CD133 Full Length Protein, His Tag (Nanodisc)
 
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CD133 分子别名

CD133,PROM1,PROML1,Prominin-1,AC133

CD133 分子背景

Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

CD133 前沿进展

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