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HGF信息

英文名称:Hepatocyte growth factor
中文名称:肝细胞生长因子
靶点别称:EC 3.4.21.7,Hepatocyte Growth Factor (Hepapoietin A; Scatter Factor),EC 3.4.21,HGF,Hepatopoietin-A,Scatter factor,Hepatocyte Growth Factor (Hepapoietin A,Scatter Factor),Fibroblast-Derived Tumor Cytotoxic Factor,Lung Fibroblast-Derived Mitogen,SF,Deafness, Autosomal Recessive 39,Hepatopoietin A,DFNB39,F-TCF,HGFB,Hepatocyte Growth Factor,HPTA
上市药物数量:1
临床药物数量:8
最高研发阶段:批准上市

HGF产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
HGF-H52H3
Human
Human HGF Protein, His Tag (MALS verified)
HGF-H5253
Human
Human HGF Protein, Fc Tag (MALS verified)
 
评论(1)
HGF-H52H3|Human HGF Protein, His Tag (MALS verified)
  1. 152XXXXXXX0
  2. 0人赞
  3. 作为刺激因子激活下游信号通路,ACRO的产品在速度上非常有优势,比国外的产品货期短很多,效果也不错,希望继续做出优质的产品
  4. >
  5. 2022-03-10
 

HGF 分子别名

HGF,HPTA,SF

HGF 分子背景

Hepatocyte growth factor (HGF) is a paracrine cellular growth, motility and morphogenic factor. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. In addition, HGF has been implicated in a variety of cancers, including of the lungs, pancreas, thyroid, colon, and breast.

HGF 前沿进展

HGF上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Beperminogene perplasmid DS-992; AMG-0001; TREAT-HGF; AMG-0001-01 批准上市 Anges Mg, 大阪大学 Collategene Japan 外周动脉疾病, 缺血 Anges, null 2019-03-01 动脉粥样硬化, 动脉闭塞性疾病, 外周血管疾病, 血管疾病, 足溃疡, 缺血, 溃疡, 外周动脉疾病 详情

HGF临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Microbiome-optimized autologous stem cell therapy (Biotech Holdings) 临床阶段不明 Biotech Holdings 外周血管疾病 详情
Ficlatuzumab AV-299; SCH-900105 Aveo 详情
YYB-101 NOV-1105; YYB-101 临床二期 Yooyoung 结直肠癌 详情
ATH-1020 ATH-1020 Athira Pharma Inc 详情
Fosgonimeton ATH-1017; NDX-1017 M3 Biotechnology 详情
MP-0250 MP-0250 Molecular Partners 详情
RNA CART-cMET (Abramson Cancer Center) 宾夕法尼亚大学 详情
Donaperminogene seltoplasmid (ViroMed) VM202-Stent; VM202-PAD; pCK-HGF-X7; VM202-DPN; VM-202CAD; VM-202ALS; VM202-RY; VM-202; NL-003; HGF-X7 临床三期 Viromed 缺血性心脏病, 糖尿病足溃疡, 间歇性跛行, 心肌梗塞, 动脉闭塞性疾病, 外周血管疾病, 糖尿病神经病变, 缺血, 糖尿病周围神经病变, 溃疡, 外周动脉疾病, 肌萎缩性侧索硬化 详情

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