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VSIG3产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
VS3-H82F9
Human
Biotinylated Human VSIG3 Protein, Fc,Avitag™
VS3-H5258
Human
Human VSIG3 Protein, Fc Tag
 
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VSIG3 分子别名

VSIG3,IgSF11,CXADRL1,Bt-IgSF,CT119

VSIG3 分子背景

VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.

VSIG3 前沿进展

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