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Fc gamma RIV / CD16-2产品列表

ACRO质量管理体系
 
评论(1)
FC4-M52H3|Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)
  1. 186XXXXXXX1
  2. 2人赞
  3. 买过你们家的各种人及鼠Fc受体,检测出的数据具有非常好的稳定性。此外,你们的蛋白在冰箱反复冻融后仍能重复出较好的数据,给你们的产品点赞!!
  4. 2019-09-26
 

Fc gamma RIV / CD16-2 分子别名

Fc gamma RIV,CD16-2,Fcgr4

Fc gamma RIV / CD16-2 分子背景

FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions

Fc gamma RIV / CD16-2 前沿进展

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