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HVEM产品列表

 
评论(2)
HVM-H5257|Human HVEM / TNFRSF14 Protein, Mouse IgG2a Fc Tag (MALS verified)
  1. 178XXXXXXX2
  2. 0人赞
  3. 该产品纯度高,结构稳定,电泳结果明显,生物活性稳定。实验过程中,使用未出现任何问题,客服态度也很好,发货快,物流快,之后还会购买。
  4. 2022-11-16
HVM-H82F6|Biotinylated Human HVEM / TNFRSF14 Protein, Fc,Avitag™ (MALS verified)
  1. 139XXXXXXX0
  2. 0人赞
  3. 该蛋白纯度高,检测过程中结合速度快,能力也比较强,非特异背景也比较低,使用实验结果符合预期,也易于储存,物流也很快。
  4. 2022-11-17
 

HVEM 分子别名

TNFRSF14,ATAR,HVEA,HVEM,LIGHTR,TR2,CD270

HVEM 分子背景

Herpesvirus entry mediator (HVEM) is also known as TNFRSF14, TR2 (TNF receptorlike molecule) and ATAR (another TRAF associated receptor), is a type I membrane protein belonging to the TNF/NGF receptor superfamily. HVEM expression has been detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. The extracellular domain of HVEM has been shown to interact directly with the herpes simplex virus envelope glycoprotein D (gD). Two TNF superfamily ligands, including the secreted TNFβ (lymphotoxin α) and the membrane protein LIGHT (lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), have been shown to be the cellular ligands for HVEM. Besides HVEM, LIGHT can also interact with LTβR, the receptor for lymphotoxin αβ heterotrimer. The role of the HVEM LIGHT /LTβ receptor ligand pair in immune function and herpesvirus pathobiology remains to be elucidated.

HVEM 前沿进展

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