PSCA 靶点蛋白|抗体药物|临床药物信息

PSCA信息

英文名称：Prostate stem cell antigen
中文名称：前列腺干细胞抗原
靶点别称：Prostate stem cell antigen，UNQ206/PRO232，PSCA，PRO232

上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

PSCA产品列表

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产品库

在线 (3)

物种

标签

属性

Protein (3)

标记

货号	物种	产品描述
PSA-H52H6	Human	Human PSCA Protein, His Tag
PSA-H82E3	Human	Biotinylated Human PSCA Protein, His,Avitag™ (MALS verified)
PSA-M82E3	Mouse	Biotinylated Mouse PSCA Protein, His,Avitag™ (MALS verified)

PSCA 分子别名

PSCA,UNQ206,PRO232

PSCA 分子背景

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

PSCA 前沿进展

PSCA临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
124-iodine-labeled PSCA targeting minibody (ImaginAb)		临床一期	加州大学洛杉矶分校	胰腺癌, 膀胱癌, 前列腺癌	详情
Anti-PSCA monoclonal antibody (Agensys)	MK-4721; AGS-PSCA; AGS-1C4D4		Agensys		详情
GEM3-PSCA	GEM3-PSCA	临床一期	Gemoab Monoconals, Gcp Service International	肾肿瘤, 移行细胞癌, 前列腺癌, 非小细胞肺癌	详情
BPX-601	BPX-601	临床二期	Bellicum	胰腺癌, 前列腺癌, 胰腺导管癌	详情

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PSCA