Properdin 靶点蛋白|抗体药物|临床药物信息

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His Tag (3)

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Protein (3)

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Unconjugated (3)

货号	物种	产品描述
PRN-H52H3	Human	Human Properdin Protein, His Tag
PRN-M52H5	Mouse	Mouse Properdin Protein, His Tag
PRN-R52H6	Rhesus macaque	Rhesus macaque Properdin Protein, His Tag

Properdin 分子别名

Properdin,Complement factor P,CFP,PFC

Properdin 分子背景

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

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Properdin

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