GM-CSF R alpha 靶点蛋白|抗体药物|临床药物信息

GM-CSF R alpha信息

英文名称：Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
中文名称：粒细胞-巨噬细胞集落刺激因子受体α亚基
靶点别称：GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR

上市药物数量：0
临床药物数量：2
最高研发阶段：临床三期

GM-CSF R alpha产品列表

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Protein (3)

标记

Unconjugated (3)

货号	物种	产品描述
GMA-M52H3	Mouse	Mouse GM-CSF R alpha Protein, His Tag
GRA-H5255	Human	Human GM-CSF R alpha Protein, Fc Tag
GRA-H52H7	Human	Human GM-CSF R alpha Protein, His Tag (SPR verified)

GRA-H5255|Human GM-CSF R alpha Protein, Fc Tag

185XXXXXXX0

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该产品用于药物发现高通量筛选， ACRO的GM-CSF与其受体具有很好的亲和力，通过SA捕获0.0625ug/ml GM-CSF,可检测4-60ng/ml GM-CSFR，能够建立稳定的筛选体系，FRET同样具有较高的亲和力。
2021-09-05

GM-CSF R alpha分子别名

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

GM-CSF R alpha分子背景

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
STSA-1005	STSA-1005; STSA1005	临床一期	舒泰神（北京）生物制药股份有限公司	新型冠状病毒肺炎	详情
Mavrilimumab	CAM-3001; KPL-301; GM-CSFR; CAM3001	临床三期	Csl Ltd	肺炎, 巨细胞性动脉炎, 类风湿关节炎, 新型冠状病毒肺炎, 冠状病毒感染	详情

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GM-CSF R alpha

GM-CSF R alpha信息

GM-CSF R alpha产品列表

GM-CSF R alpha分子别名

GM-CSF R alpha分子背景

GM-CSF R alpha临床药物信息

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