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 > 【Vitronectin】

Vitronectin信息

英文名称:Vitronectin
中文名称:玻连蛋白
靶点别称:Somatomedin B,Epibolin,Serum Spreading Factor,VNT,S-protein,Complement S-Protein,Vitronectin,V75,VN,Serum-spreading factor,Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein)
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

Vitronectin 分子别名

VTN,V75,VN,Vitronectin,S-protein,Serum-spreading factor

Vitronectin 分子背景

Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.

Vitronectin 前沿进展

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