GFR alpha-like 靶点蛋白|抗体药物|临床药物信息

GFR alpha-like信息

英文名称：GDNF family receptor alpha-like
中文名称：
靶点别称：

上市药物数量：0
临床药物数量：0
最高研发阶段：终止

GFR alpha-like产品列表

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在线 (6)

物种

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属性

Protein (6)

标记

Unconjugated (6)

货号	物种	产品描述
GFA-H52H3	Human	Human GFR alpha-like Protein, His Tag
GFA-C52H6	Cynomolgus	Cynomolgus GFR alpha-like Protein, His Tag
GFA-M52H7	Mouse	Mouse GFR alpha-like Protein, His Tag
GFA-R52H5	Rat	Rat GFR alpha-like Protein, His Tag
GFE-H5259	Human	Human GFR alpha-like Protein, Fc Tag
GFA-R52H7	Rhesus macaque	Rhesus macaque GFR alpha-like Protein, His Tag

GFR alpha-like 分子别名

GFR alpha like,GFR alpha-like,GFRAL,GRAL

GFR alpha-like 分子背景

GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor α-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.

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GFR alpha-like

GFR alpha-like信息

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GFR alpha-like 分子别名

GFR alpha-like 分子背景

GFR alpha-like 前沿进展

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