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Fc gamma RIIIA / CD16a信息

英文名称:Low affinity immunoglobulin gamma Fc region receptor III-A
中文名称:低亲和力免疫球蛋白γFc段受体III-A
靶点别称:Fc Fragment Of IgG, Low Affinity IIIa, Receptor (CD16a),CD16a Antigen,IGFR3,FCG3,Fc Fragment Of IgG, Low Affinity IIIa, Receptor For (CD16),Fc Fragment Of IgG, Low Affinity III, Receptor For (CD16),Immunoglobulin G Fc Receptor III,Fc-Gamma Receptor III-2 (CD 16),Neutrophil-Specific Antigen NA,Fc-Gamma Receptor IIIb (CD16),Fc Gamma Receptor III-A,Fc Gamma Receptor IIIa,Fc-Gamma RIIIa,Fc-Gamma RIII,FCGRIII,FcRIIIa,FCR-10,FCRIII,IMD20,CD16,Low affinity immunoglobulin gamma Fc region receptor III-A,
上市药物数量:0
临床药物数量:5
最高研发阶段:临床二期

Fc gamma RIIIA / CD16a产品列表

 
评论(17)
CD8-H52H4|Human Fc gamma RIIIA / CD16a (V176) Protein, His Tag (SPR & BLI & MALS verified)
  1. 189XXXXXXX3
  2. 1人赞
  3. 采购该蛋白CD8-H52H4,用于ELISA,抗体与受体的Fc受体亲和力的检测,阳参抗体SPR与ELISA结合实验结果符合预期。客服人员服务态度很好,很耐心,下一次继续考虑
  4. 2022-05-09
CDA-H82E8|Biotinylated Human Fc gamma RIIIA / CD16a (F176) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)
  1. 178XXXXXXX2
  2. 1人赞
  3. 这个是表征分析的必须要蛋白CD16A(F176)这个蛋白与CD16A(V176)是人种的不同 表征分析的时候两个都需要做 抗体或者ADC的表征分析(受体与抗体)亲和力大小 活性好才是真的好,我已经第三次购买这个蛋白 活性特别好
  4. 2022-04-22
CDA-H82E9|Biotinylated Human Fc gamma RIIIA / CD16a (V176) Protein, Avitag™,His Tag (SPR & BLI verified)
  1. 178XXXXXXX2
  2. 0人赞
  3. 这个是表征分析的必须要蛋白CD16A(V176) 抗体或者ADC的表征分析(受体与抗体)亲和力大小 活性好才是真的好,我已经第三次购买这个蛋白 活性特别好 比其它国产的好很多
  4. 2022-04-22
 

Fc gamma RIIIA / CD16a 分子别名

FCGR3A,CD16A,FCG3,FCGR3,IGFR3

Fc gamma RIIIA / CD16a 分子背景

CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody­dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.

Fc gamma RIIIA / CD16a 前沿进展

Fc gamma RIIIA / CD16a临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AFM-13 AFM-13 临床二期 德州大学安德森癌症中心 周围T-细胞淋巴瘤, 霍奇金病, 非霍奇金淋巴瘤, 蕈样真菌病 详情
AFM-24 AFM-24 临床二期 Affimed 实体瘤, 头颈部鳞状细胞癌, 结直肠癌, 非小细胞肺癌, 转移癌 详情
FT-536 FT-536 临床一期 Fate Therapeutics Inc 实体瘤 详情
FT-538 FT-538 临床一期 Fate Therapeutics 实体瘤, 急性髓细胞样白血病 详情
FT-596 FT-596 临床一期 Fate Therapeutics Inc B-细胞淋巴瘤, 急性髓细胞样白血病, 慢性淋巴细胞白血病 详情
OXS-3550 GTB-3550; OXS-3550; OXIS-3550; 161533-TriKE; 161533 TriKE; OXS-3550-TriKE 临床二期 University Of Minnesota, Oxis Biotech 骨髓增生异常综合征, 系统性肥大细胞增多症, 肥大细胞白血病, 急性髓细胞样白血病 详情
FT-576 FT-576 临床一期 University Of Minnesota, Fate Therapeutics Inc 骨髓肿瘤, 多发性骨髓瘤 详情

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