登录 | 注册    关注公众号  
微信公众号
搜索

Fc gamma RIIIA / CD16a信息

英文名称:Low affinity immunoglobulin gamma Fc region receptor III-A
中文名称:低亲和力免疫球蛋白γFc段受体III-A
靶点别称:Fc Fragment Of IgG, Low Affinity IIIa, Receptor (CD16a),CD16a Antigen,IGFR3,FCG3,Fc Fragment Of IgG, Low Affinity IIIa, Receptor For (CD16),Fc Fragment Of IgG, Low Affinity III, Receptor For (CD16),Immunoglobulin G Fc Receptor III,Fc-Gamma Receptor III-2 (CD 16),Neutrophil-Specific Antigen NA,Fc-Gamma Receptor IIIb (CD16),Fc Gamma Receptor III-A,Fc Gamma Receptor IIIa,Fc-Gamma RIIIa,Fc-Gamma RIII,FCGRIII,FcRIIIa,FCR-10,FCRIII,IMD20,CD16,Low affinity immunoglobulin gamma Fc region receptor III-A,
上市药物数量:0
临床药物数量:5
最高研发阶段:临床二期

Fc gamma RIIIA / CD16a产品列表

 
评论(20)
CDA-H5220|Human Fc gamma RIIIA / CD16a (F176) Protein, His Tag (SPR & BLI & MALS verified)
  1. 158XXXXXXX6
  2. 6人赞
  3. 我们购买了测定Fc受体相关的几个受体蛋白,主要用于FC受体fortebio亲和力的测定,考察抗体与FC受体结合强弱,与同类产品的其他品牌蛋白相比,纯度和活性都比较好,而且物流快,发货及时。希望以后有其他产品的采购!
  4. 2019-10-16
CDA-H5220|Human Fc gamma RIIIA / CD16a (F176) Protein, His Tag (SPR & BLI & MALS verified)
  1. 136XXXXXXX0
  2. 3人赞
  3. 我们做SPR需要用的这个蛋白,做FC通用的检测项目需要用到这CD16 V 模式的强binding, 按照Acro的大概实验流程,很容易就检测出来分子结合,这个蛋白好使!!!
  4. 2020-12-01
CD8-H52H4|Human Fc gamma RIIIA / CD16a (V176) Protein, His Tag (SPR & BLI & MALS verified)
  1. 158XXXXXXX9
  2. 2人赞
  3. 这个产品性能比较稳定,在酶联免疫实验中,亲和力较强,节省了我们大量实验时间,项目组也挺认可,以后也会多多关注该公司其他产品
  4. 2022-01-12
 

Fc gamma RIIIA / CD16a 分子别名

FCGR3A,CD16A,FCG3,FCGR3,IGFR3

Fc gamma RIIIA / CD16a 分子背景

CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody­dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.

Fc gamma RIIIA / CD16a 前沿进展

Fc gamma RIIIA / CD16a临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
SM-3321 SM-3321 临床一期 北京烁星生物医药科技有限公司 急性髓细胞样白血病 详情
FT-516 FT-516 University Of Minnesota, Fate Therapeutics Inc 详情
FT-538 FT-538 Fate Therapeutics 详情
FT-596 FT-596 临床一期 Fate Therapeutics Inc B-细胞淋巴瘤, 慢性淋巴细胞白血病 详情
OXS-3550 OXS-3550-TriKE; GTB-3550; OXS-3550; OXIS-3550; 161533-TriKE; 161533 TriKE Oxis Biotech, University Of Minnesota 详情
AFM-24 AFM-24 Affimed 详情
GMA-161 GMA-161 临床一期 赛诺菲, Macrogenics 特发性血小板减少性紫癜 详情
AFM-13 AFM-13 临床二期 德州大学安德森癌症中心 周围T-细胞淋巴瘤, 霍奇金病, 蕈样真菌病 详情

消息提示

请输入您的联系方式,再点击提交!

确定