搜索
 > 【Fc gamma RIIA / CD32a】

Fc gamma RIIA / CD32a信息

英文名称:Low affinity immunoglobulin gamma Fc region receptor II-a
中文名称:低亲和力免疫球蛋白γFc区受体II-a
靶点别称:Fc Gamma Receptor RIIa3,IgG Fc receptor II-a,CDw32,Fc-gamma-RIIa,Low affinity immunoglobulin gamma Fc region receptor II-a,FCGR2A1,Fc-gamma RII-a,CD32,FCGR2A,Fc Fragment Of IgG Receptor IIa,Fc Fragment Of IgG, Low Affinity IIa, Receptor (CD32),Immunoglobu
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

Fc gamma RIIA / CD32a产品列表

 
评论(3)
CDA-H82E6|Biotinylated Human Fc gamma RIIA / CD32a (H167) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)
  1. 158XXXXXXX1
  2. 0人赞
  3. 检测后从结果上分析和之前的结果相比基本上是同样的趋势,复溶之后放-80度冰箱,再次使用,对结果没什么影响,稳定性好。
  4. 2021-10-26
CD1-H5223|Human Fc gamma RIIA / CD32a (H167) Protein, His Tag (SPR & BLI & MALS verified)
  1. 166XXXXXXX7
  2. 0人赞
  3. FCγR系列产品/CD32a(H167),HIS Tag主要与ADCP功能有关,因而检测与其亲和力强弱,结果数量级与文献报道一致。
  4. 2021-09-27
CDA-H82E6|Biotinylated Human Fc gamma RIIA / CD32a (H167) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)
  1. 134XXXXXXX1
  2. 1人赞
  3. CDA-H82E6抗原用来检测抗体的亲和力,由结果得知抗原稳定性好,多次采购价格优惠,质量很好。
  4. 2021-09-06
 

Fc gamma RIIA / CD32a 分子别名

CD32a,FCGR2A,CD32,FCG2 ,FCGR2A1,IGFR2

Fc gamma RIIA / CD32a 分子背景

Receptors for the Fc region of IgG (Fc γ R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc γ Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. The activating isoform, CD32A, is expressed on monocytes, neutrophils, platelets and dendritic cells. CD32A is expressed on many immune cell types (macrophage, neutrophil, eosinophils, platelets, dendritic cells and Langerhan cells), where inhibitory ITIM­bearing receptors may also be coexpressed and co­engaged by specific ligands. CD32A delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation and cytokine production. The responses can be modulated by signals from the coexpressed inhibitory receptors such as CD32B, and the strength of the signal is dependent on the ratio of expression of the activating and inhibitory receptors.

Fc gamma RIIA / CD32a 前沿进展

Fc gamma RIIA / CD32a临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
VIB-9600 VIB-9600; MEDI-9600 临床一期 Medimmune Llc, Viela Bio 自身免疫疾病 详情

消息提示

请输入您的联系方式,再点击提交!

确定