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Fc gamma RIIA / CD32a信息

英文名称:Low affinity immunoglobulin gamma Fc region receptor II-a
中文名称:低亲和力免疫球蛋白γFc区受体II-a
靶点别称:Low affinity immunoglobulin gamma Fc region receptor II-a,FCGR2A1,Fc-gamma RII-a,CD32,FCGR2A,Fc Fragment Of IgG Receptor IIa,Fc Fragment Of IgG, Low Affinity IIa, Receptor (CD32),Immunoglobulin G Fc Receptor II,IGFR2,FCG2,Fc Fragment Of IgG, Low Affinity IIa, Receptor For (CD32),Fc Gamma Receptor IIa,CD32 Antigen,CD32A,FCGR2,IgG Fc receptor II-a,CDw32,Fc-gamma-RIIa,FcRII-a,FcGR,Fc Gamma Receptor RIIa3
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

Fc gamma RIIA / CD32a产品列表

 
评论(12)
CDA-H82E6|Biotinylated Human Fc gamma RIIA / CD32a (H167) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)
  1. 178XXXXXXX2
  2. 3人赞
  3. 这是CD32A蛋白 这个蛋白也是抗体与受体亲和力分析的必须蛋白 表征申报的必须要测项目 活性好是我的选择之一 绝对好用
  4. 2022-04-22
CDA-H82E6|Biotinylated Human Fc gamma RIIA / CD32a (H167) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)
  1. 159XXXXXXX3
  2. 2人赞
  3. 我们在实验中进行方法构建,实验的结果非常好,结果表明,这一抗原稳定性好,而且反复使用的重复性也好,大大增加了实验的成功率。
  4. 2022-01-14
CD1-H5223|Human Fc gamma RIIA / CD32a (H167) Protein, His Tag (SPR & BLI & MALS verified)
  1. 182XXXXXXX0
  2. 2人赞
  3. 抗体很好用,实验结果很好,物流很快,配送用顺丰,很棒;客服技术人员态度好,沟通有效,回复快,给予了很多帮助,非常好啦啦
  4. 2022-05-09
 

Fc gamma RIIA / CD32a 分子别名

CD32a,FCGR2A,CD32,FCG2 ,FCGR2A1,IGFR2

Fc gamma RIIA / CD32a 分子背景

Receptors for the Fc region of IgG (Fc γ R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc γ Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. The activating isoform, CD32A, is expressed on monocytes, neutrophils, platelets and dendritic cells. CD32A is expressed on many immune cell types (macrophage, neutrophil, eosinophils, platelets, dendritic cells and Langerhan cells), where inhibitory ITIM­bearing receptors may also be coexpressed and co­engaged by specific ligands. CD32A delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation and cytokine production. The responses can be modulated by signals from the coexpressed inhibitory receptors such as CD32B, and the strength of the signal is dependent on the ratio of expression of the activating and inhibitory receptors.

Fc gamma RIIA / CD32a 前沿进展

Fc gamma RIIA / CD32a临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
VIB-9600 VIB-9600; MEDI-9600 临床一期 Medimmune Llc, Viela Bio, Horizon Therapeutics Plc 自身免疫疾病 详情
QLS-21908 QLS-21908 临床一期 齐鲁制药有限公司 自身免疫疾病 详情

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